Brewers vs Padres Prediction, Odds, Moneyline, Spread & Over/Under for NLDS Game 1 on Oct. 3

Odds updated as of 8:11 p.m.

The Milwaukee Brewers versus the San Diego Padres in Game 1 of the NLDS is on the MLB schedule for Saturday.

All the info you need to make smart bets on this matchup at FanDuel Sportsbook can be found below. Check out all of the latest MLB betting lines here.

Brewers vs Padres Game Info

• Milwaukee Brewers (103-59) vs. San Diego Padres (91-71)
• Date: Saturday, October 3, 2026
• Time: 8:30 p.m. ET
• Venue: American Family Field -- Milwaukee, Wisconsin
• Coverage: Fox Sports 1

Brewers vs Padres Odds & Moneyline

• All MLB odds, betting lines and prop bets are available on FanDuel Sportsbook.
• Moneyline: MIL: (-200) | SD: (+180)
• Spread: MIL: -1.5 (+105) | SD: +1.5 (-126)
• Total: 6.5 -- Over: (-144) | Under: (+118)

Brewers vs Padres Probable Starting Pitchers

Probable Pitchers: Jacob Misiorowski (Brewers) - 16-5, 1.80 ERA vs Robbie Ray (Padres) - 13-8, 3.59 ERA

The Brewers will call on Jacob Misiorowski (16-5, 1.80 ERA) against the Padres and Robbie Ray (13-8, 3.59 ERA). Misiorowski and his team have a record of 19-11-0 against the spread when he starts. Misiorowski's team has been victorious in 77.8% of the games he's started as the moneyline favorite with a record of 21-6. When Ray starts, the Padres are 18-10-0 against the spread. The Padres have been the moneyline underdog in 13 of Ray's starts this season, and they went 6-7 in those games.

Brewers vs Padres Prediction & Pick

All MLB win probability predictions and picks are according to numberFire.
Prediction: Brewers win (62.6%)

Brewers vs Padres Moneyline

• The Brewers vs Padres moneyline has Milwaukee as a -200 favorite, while San Diego is a +180 underdog on the road.

Brewers vs Padres Spread

• The Brewers are favored by 1.5 runs at home versus the Padres. The Brewers are +105 to cover the spread, while the Padres are -126.

Brewers vs Padres Over/Under

• A combined run total of 6.5 has been set for Brewers-Padres on Oct. 3, with the over at -144 and the under at +118.

Bet on Milwaukee Brewers vs. San Diego Padres on FanDuel today!

Brewers vs Padres Betting Trends

• The Brewers have come away with 82 wins in the 125 contests they have been listed as the favorites in this season.
• Milwaukee has a record of 18-5 when favored by -200 or more this year.
• The Brewers' games have gone over the total in 71 of their 161 opportunities.
• In 161 games with a line this season, the Brewers have a mark of 84-77-0 against the spread.
• The Padres have won 49.4% of the games this season they were the underdog on the moneyline (38-39).
• San Diego has a 2-4 record (winning just 33.3% of its games) when it has played as a moneyline underdog of +180 or longer.
• The Padres have played in 164 games with a set over/under, and have combined with opponents to go over the total 78 times (78-83-3).
• The Padres are 96-68-0 ATS this season.

Brewers Player Leaders

• Brice Turang leads Milwaukee in slugging percentage (.452) thanks to 61 extra-base hits. He has a .270 batting average and an on-base percentage of .367.
• He ranks 41st in batting average, 19th in on-base percentage, and 47th in slugging among qualified hitters in baseball.
• Turang hopes to build on a six-game hitting streak in this matchup. During his last 10 outings he is batting .310 with four doubles, two home runs, three walks and eight RBIs.
• William Contreras has 27 doubles, a triple, 18 home runs and 61 walks. He's batting .270 and slugging .417 with an on-base percentage of .341.
• Among all qualifying players, he ranks 41st in batting average, 54th in on-base percentage and 77th in slugging percentage.
• Contreras heads into this matchup looking to extend his two-game hit streak. During his last five outings he is batting .235 with two walks and six RBIs.
• Jackson Chourio has 152 hits and is batting .291 this season.
• Chourio enters this matchup with five games in a row with at least one hit. During his last five outings he is hitting .571 with a home run, two walks and five RBIs.
• Jake Bauers has 127 hits this season and a team-best OBP of .389.

Padres Player Leaders

• Fernando Tatis Jr. has put up a slugging percentage of .470, a team-high for the Padres. He's batting .289 with an on-base percentage of .358.
• Including all the qualified hitters in the big leagues, his batting average places him 13th, his on-base percentage ranks 36th, and he is 34th in slugging.
• Jackson Merrill is hitting .254 with 26 doubles, five triples, 26 home runs and 41 walks. He's slugging .440 with an on-base percentage of .303.
• Including all qualifying hitters, he is 74th in batting average, 113th in on-base percentage and 56th in slugging percentage.
• Manny Machado is batting .217 with 22 doubles, 30 home runs and 76 walks.
• Xander Bogaerts has 18 doubles, a triple, 13 home runs and 77 walks while batting .231.

Brewers vs Padres Head to Head

• 8/12/2026: 4-3 SD (Favorite: Brewers, Spread: -1.5, Total: 8, Favorite Moneyline: -116, Underdog Moneyline: +108)
• 8/11/2026: 11-2 SD (Favorite: Brewers, Spread: -1.5, Total: 7.5, Favorite Moneyline: -126, Underdog Moneyline: +116)
• 8/10/2026: 3-2 SD (Favorite: Brewers, Spread: -1.5, Total: 7, Favorite Moneyline: -120, Underdog Moneyline: +110)
• 5/14/2026: 7-1 MIL (Favorite: Brewers, Spread: -1.5, Total: 7.5, Favorite Moneyline: -134, Underdog Moneyline: +114)
• 5/13/2026: 3-1 SD (Favorite: Brewers, Spread: -1.5, Total: 7, Favorite Moneyline: -156, Underdog Moneyline: +132)
• 5/12/2026: 6-4 MIL (Favorite: Brewers, Spread: -1.5, Total: 8.5, Favorite Moneyline: -146, Underdog Moneyline: +124)
• 9/24/2025: 3-1 MIL (Favorite: Padres, Spread: -1.5, Total: 7.5, Favorite Moneyline: -142, Underdog Moneyline: +120)
• 9/23/2025: 7-0 SD (Favorite: Brewers, Spread: -1.5, Total: 8, Favorite Moneyline: -118, Underdog Moneyline: -100)
• 9/22/2025: 5-4 SD (Favorite: Brewers, Spread: -1.5, Total: 7, Favorite Moneyline: -110, Underdog Moneyline: -106)
• 6/8/2025: 1-0 SD (Favorite: Brewers, Spread: -1.5, Total: 8.5, Favorite Moneyline: -172, Underdog Moneyline: +144)

Sign up for FanDuel Sportsbook and FanDuel Daily Fantasy today!