Duke vs Pittsburgh College Basketball Prediction, Odds, Picks, Best Bets for Feb. 10

The Pittsburgh Panthers (9-15, 2-9 ACC) will attempt to end a three-game losing streak when they host the Duke Blue Devils (21-2, 10-1 ACC) on February 10, 2026 at Petersen Events Center.

Before you place your bet on this matchup at FanDuel Sportsbook, here are the NCAA basketball odds and spreads you need to know.

Duke vs. Pittsburgh Game Info and Odds

• Game day: Tuesday, February 10, 2026
• Game time: 9 p.m. ET
• TV channel: ESPN
• Location: Pittsburgh, Pennsylvania
• Arena: Petersen Events Center

Duke vs. Pittsburgh Picks and Prediction

All college basketball win probability predictions and picks are according to numberFire.
Prediction: Duke win (87.3%)

See the betting trends and insights below before making a bet on Tuesday's Duke-Pittsburgh spread (Duke -16.5) or total (136.5 points).

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Duke vs. Pittsburgh: ATS Betting Stats and Trends

• Duke is 12-11-0 ATS this season.
• Pittsburgh has won 10 games against the spread this season, while failing to cover 14 times.
• The Blue Devils have covered the spread in a lower percentage of their home games than away games. They have covered four times in 11 games when playing at home, and they've covered six times in eight games on the road.
• Against the spread, the Panthers have had better results on the road (3-4-0) than at home (6-9-0).
• Duke is 6-5-0 against the spread in conference play this year.
• Pittsburgh has four wins against the spread in 11 ACC games this year.

Duke vs. Pittsburgh: Moneyline Betting Stats

• Duke has come away with 15 wins in the 17 contests it has been listed as the moneyline favorite in this season.
• The Blue Devils have been a -2778 moneyline favorite on three occasions this season and won every game.
• Pittsburgh has won 16.7% of the games this season it was the underdog on the moneyline (2-10).
• The Panthers have yet to play as a moneyline underdog of +1160 or longer.
• The moneyline set for this matchup implies Duke has a 96.5% chance of walking away with the win.

Duke vs. Pittsburgh Head-to-Head Comparison

• Duke was the 11th-best team in the nation in points scored (83.2 per game) and seventh-best in points allowed (62.8) last year.
• Duke was the 24th-best team in the country in rebounds per game (35.6) and 12th-best in rebounds conceded (27.3) last season.
• Duke was 17th-best in college basketball in assists (16.9 per game) last season.
• Duke was the ninth-best squad in college basketball in turnovers per game (8.9) and 265th in turnovers forced (10.4) last year.
• On offense, Pittsburgh scored 75.9 points per game (119th-ranked in college basketball) last year. It surrendered 70.8 points per contest at the other end (140th-ranked).
• Last season Pittsburgh grabbed 30.6 rebounds per game (266th-ranked in college basketball) and gave up 30.5 rebounds per contest (135th-ranked).
• Pittsburgh delivered 13.4 dimes per game, which ranked them 196th in college basketball.
• With 9.7 turnovers per game, Pittsburgh was 45th in college basketball. It forced 11.7 turnovers per contest, which ranked 140th in college basketball.

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