Devils vs Sabres NHL Prediction, Odds, Picks, Best Bets for Dec. 21

The NHL slate on Sunday includes the New Jersey Devils taking on the Buffalo Sabres.

We've got you covered, in terms of the most important info regarding NHL betting lines, before you make your wager on FanDuel Sportsbook.

Devils vs Sabres Game Info

• New Jersey Devils (20-14-1) vs. Buffalo Sabres (16-14-4)
• Date: Sunday, December 21, 2025
• Time: 7 p.m. ET
• Venue: Prudential Center -- Newark, New Jersey
• Coverage: ESPN+

Devils vs Sabres Odds

All NHL odds, betting lines and prop bets are available on FanDuel Sportsbook.

Devils vs Sabres Prediction & Pick

All NHL win probability predictions and picks are according to numberFire.

• Prediction: Devils win (63.2%)

Devils vs Sabres Puck Line

• The Sabres are underdogs by 1.5 goals on the road against the Devils. The Sabres are -178 to cover the spread, and the Devils are +144.

Devils vs Sabres Over/Under

• The Devils-Sabres game on Dec. 21 has been given an over/under of 6.5 goals. The over is -110 and the under is -110.

Devils vs Sabres Moneyline

• The Devils vs Sabres moneyline has New Jersey as a -162 favorite, while Buffalo is a +134 underdog on the road.

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