Derrick Henry Fantasy Football Week 1: Stats and Projections vs. Bills

Baltimore Ravens RB Derrick Henry will take on the team with last season's 12th-ranked run defense, the Buffalo Bills (115.5 yards allowed per game), in Week 1 -- beginning at 8:20 p.m. ET on Sunday.

For more information on Henry, if you're considering him for your daily fantasy roster, scroll down prior to his upcoming game against the Bills.

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Derrick Henry Week 1 Fantasy Football Projection

• Matchup: Baltimore Ravens at Buffalo Bills
• Game Date: September 7, 2025
• Game Time: 8:20 p.m.
• Projected Fantasy Points: 12.5
• PPR Projected Fantasy Points: 12.7
• Projected Rushing Yards: 81.76
• Projected Rushing TDs: 0.65
• Projected Receiving Yards: 4.00
• Projected Receiving TDs: 0.03

Projections provided by numberFire

Henry 2024 Fantasy Performance

• Henry accumulated 32.9 fantasy points -- 24 carries, 199 yards, 1 TD; 3 receptions, 10 yards, 1 TD -- in Week 4 against the Buffalo Bills, which was his best game last year.
• In Week 1 against the Pittsburgh Steelers, Henry put up 30.6 fantasy points (his second-best total last year), via these numbers: 26 carries, 186 yards, 2 TDs.
• In his worst game of the season -- Week 15 versus the New York Giants -- Henry accumulated 6.7 fantasy points. His stat line was: 14 carries, 67 yards.
• In his second-worst performance of the year -- Week 11 against the Pittsburgh Steelers -- Henry had 10.5 fantasy points. His stat line: 13 carries, 65 yards, 1 TD.

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Bills Defensive Performance

• Last season, Buffalo allowed only three quarterbacks to amass more than 300 passing yards in a game.
• The Bills surrendered at least one passing touchdown to 15 opposing QBs last season.
• In the passing game, Buffalo allowed nine players to throw at least two touchdowns in a game last year.
• In the passing game, the Bills surrendered at least three passing touchdowns to just two opposing quarterbacks last year.
• Versus Buffalo last season, six players put up more than 100 receiving yards in a game.
• In terms of pass defense, the Bills gave up a touchdown reception to 27 players last season.
• Buffalo allowed two or more receiving touchdowns through the air to just one player last season.
• Looking at run D, the Bills yielded more than 100 yards on the ground to only three players last season.
• In terms of run defense, Buffalo gave up at least one rushing touchdown to 12 players last season.
• In the running game, the Bills allowed only one player to score at least two rushing touchdowns against them last year.

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