Cubs vs Pirates Prediction, Odds, Moneyline, Spread & Over/Under for Sept. 11

Odds updated as of 2:12 p.m.

The Friday slate in MLB includes a matchup between the Chicago Cubs and the Pittsburgh Pirates.

Before checking out the MLB betting lines on FanDuel Sportsbook, we've got you covered, in terms of the vital information about this game.

Cubs vs Pirates Game Info

• Chicago Cubs (81-66) vs. Pittsburgh Pirates (74-73)
• Date: Friday, September 11, 2026
• Time: 2:20 p.m. ET
• Venue: Wrigley Field -- Chicago, Illinois
• Coverage: MARQ and SportsNet PT

Cubs vs Pirates Odds & Moneyline

• All MLB odds, betting lines and prop bets are available on FanDuel Sportsbook.
• Moneyline: CHC: (-190) | PIT: (+160)
• Spread: CHC: -1.5 (+112) | PIT: +1.5 (-134)
• Total: 8.5 -- Over: (-104) | Under: (-118)

Cubs vs Pirates Probable Starting Pitchers

Probable Pitchers: Shota Imanaga (Cubs) - 9-10, 3.91 ERA vs Wilber Dotel (Pirates) - 1-4, 4.41 ERA

The probable pitchers are Shota Imanaga (9-10) for the Cubs and Wilber Dotel (1-4) for the Pirates. Imanaga's team is 12-15-0 against the spread this season in his starts. Imanaga's team has been victorious in 54.2% of the games he's started as the moneyline favorite with a record of 13-11. Dotel never pitched as a moneyline underdog a season ago.

Cubs vs Pirates Prediction & Pick

All MLB win probability predictions and picks are according to numberFire.
Prediction: Cubs win (53.7%)

Cubs vs Pirates Moneyline

• The Cubs vs Pirates moneyline has Chicago as a -190 favorite, while Pittsburgh is a +160 underdog on the road.

Cubs vs Pirates Spread

• The Pirates are at +1.5 on the runline against the Cubs. The Pirates are -134 to cover the spread, and the Cubs are +112.

Cubs vs Pirates Over/Under

• An over/under of 8.5 has been set for Cubs-Pirates on Sept. 11, with the over being -104 and the under -118.

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Cubs vs Pirates Betting Trends

• The Cubs have been victorious in 53, or 56.4%, of the 94 contests they have been chosen as favorites in this season.
• Chicago has a record of 7-4 in contests when oddsmakers favor them by -190 or more on the moneyline.
• The Cubs' games have gone over the total in 79 of their 142 opportunities.
• The Cubs have an against the spread mark of 68-74-0 in 142 games with a line this season.
• The Pirates have been the underdog on the moneyline 67 total times this season. They've finished 30-37 in those games.
• When it has played as a moneyline underdog with odds of +160 or longer, Pittsburgh has a 1-4 record (winning just 20% of its games).
• The Pirates have played in 145 games with an over/under set, and have combined with their opponents to go over the total 75 times (75-66-4).
• The Pirates have collected a 70-75-0 record ATS this season (covering 48.3% of the time).

Cubs Player Leaders

• Pete Crow-Armstrong has 159 hits and an OBP of .375 to go with a slugging percentage of .572. All three of those stats lead Chicago hitters this season. He has a .281 batting average, as well.
• Among the qualifying hitters in the majors, his batting average ranks 23rd, his on-base percentage ranks ninth, and he is second in slugging.
• Crow-Armstrong will look for his ninth straight game with a hit in this matchup. In his last 10 games he is hitting .256 with a double, three home runs, five walks and six RBIs.
• Alex Bregman is hitting .260 with 29 doubles, a triple, 24 home runs and 71 walks. He's slugging .440 with an on-base percentage of .349.
• Among qualifying hitters, he ranks 58th in batting average, 44th in on-base percentage and 55th in slugging percentage.
• Seiya Suzuki has 131 hits this season and has a slash line of .267/.366/.475.
• Nico Hoerner is batting .266 with a .318 OBP and 65 RBI for Chicago this season.
• Hoerner takes a two-game hitting streak into this game. In his last five games he is batting .333 with two RBIs.

Pirates Player Leaders

• Bryan Reynolds has put up an on-base percentage of .369, a team-best for the Pirates. He's batting .264 and slugging .426.
• Including all the qualifying hitters in the big leagues, his batting average ranks 55th, his on-base percentage is 17th, and he is 65th in slugging.
• Brandon Lowe's 138 hits lead his team. He has a batting average of .257 while slugging .476 with an on-base percentage of .326.
• Including all qualified players, his batting average places him 66th, his on-base percentage is 71st, and he is 26th in slugging.
• Nick Gonzales has racked up a team-best .393 slugging percentage.
• Oneil Cruz is hitting .276 with 12 doubles, a triple, 18 home runs and 41 walks.

Cubs vs Pirates Head to Head

• 7/26/2026: 8-7 PIT (Favorite: Pirates, Spread: -1.5, Total: 9, Favorite Moneyline: -132, Underdog Moneyline: +112)
• 7/25/2026: 11-0 CHC (Favorite: Pirates, Spread: -1.5, Total: 8, Favorite Moneyline: -120, Underdog Moneyline: +102)
• 7/24/2026: 3-2 CHC (Favorite: Pirates, Spread: -1.5, Total: 8, Favorite Moneyline: -108, Underdog Moneyline: -108)
• 5/28/2026: 7-2 CHC (Favorite: Pirates, Spread: -1.5, Total: 7.5, Favorite Moneyline: -174, Underdog Moneyline: +146)
• 5/27/2026: 10-4 CHC (Favorite: Pirates, Spread: -1.5, Total: 8.5, Favorite Moneyline: -122, Underdog Moneyline: +104)
• 5/26/2026: 12-1 PIT (Favorite: Pirates, Spread: -1.5, Total: 8.5, Favorite Moneyline: -134, Underdog Moneyline: +114)
• 5/25/2026: 2-1 PIT (Favorite: Cubs, Spread: -1.5, Total: 8, Favorite Moneyline: -124, Underdog Moneyline: +106)
• 4/12/2026: 7-6 CHC (Favorite: Cubs, Spread: -1.5, Total: 12.5, Favorite Moneyline: -134, Underdog Moneyline: +116)
• 4/11/2026: 4-3 PIT (Favorite: Cubs, Spread: -1.5, Total: 6.5, Favorite Moneyline: -144, Underdog Moneyline: +122)
• 4/10/2026: 2-0 PIT (Favorite: Cubs, Spread: -1.5, Total: 6.5, Favorite Moneyline: -152, Underdog Moneyline: +128)

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