Cubs vs Brewers Prediction, Odds, Moneyline, Spread & Over/Under for NLDS Game 3 on Oct. 8

Odds updated as of 1:12 a.m.

The Wednesday slate in the MLB includes a matchup between the Chicago Cubs and the Milwaukee Brewers in Game 3 of the NLDS.

Before you do any MLB betting on this matchup at FanDuel Sportsbook, here's what you need to know.

Cubs vs Brewers Game Info

• Chicago Cubs (92-70) vs. Milwaukee Brewers (97-65)
• Date: Wednesday, October 8, 2025
• Time: 5:08 p.m. ET
• Venue: Wrigley Field -- Chicago, Illinois
• Coverage: truTV, TBS, and HBO Max

Cubs vs Brewers Odds & Moneyline

• All MLB odds, betting lines and prop bets are available on FanDuel Sportsbook.
• Moneyline: CHC: (-120) | MIL: (+102)
• Spread: CHC: +1.5 (-220) | MIL: -1.5 (+180)
• Total: 6.5 -- Over: (-118) | Under: (-104)

Cubs vs Brewers Probable Starting Pitchers

Probable Pitchers: Jameson Taillon (Cubs) - 11-7, 3.68 ERA vs Quinn Priester (Brewers) - 13-3, 3.32 ERA

The probable pitchers are Jameson Taillon (11-7, 3.68 ERA) for the Cubs and Quinn Priester (13-3, 3.32 ERA) for the Brewers. Taillon's team is 12-10-0 against the spread in his starts this season. Taillon's team has been victorious in 73.3% of the games he's started as the moneyline favorite with a record of 11-4. The Brewers have a 15-9-0 record against the spread in Priester's starts. The Brewers have been the moneyline underdog in 11 of Priester's starts this season, and they went 7-4 in those games.

Cubs vs Brewers Prediction & Pick

All MLB win probability predictions and picks are according to numberFire.
Prediction: Cubs win (57.7%)

Cubs vs Brewers Moneyline

• Looking at the moneyline for Cubs-Brewers, Chicago is the favorite at -120, and Milwaukee is +102 playing on the road.

Cubs vs Brewers Spread

• The Brewers are 1.5-run favorites against the spread for this matchup with the Cubs. The Brewers are +180 to cover, while the Cubs are -220 to cover as a 1.5-run underdog on the runline.

Cubs vs Brewers Over/Under

• An over/under of 6.5 has been set for Cubs-Brewers on Oct. 8, with the over being -118 and the under -104.

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Cubs vs Brewers Betting Trends

• The Cubs have come away with 72 wins in the 111 contests they have been listed as the favorites in this season.
• Chicago has a record of 66-30 in contests when oddsmakers favor them by -120 or more on the moneyline.
• The Cubs and their opponents have hit the over in 76 of their 162 games with a total set by oddsmakers this season.
• The Cubs have posted a record of 77-85-0 against the spread this season.
• The Brewers have been the underdog on the moneyline 60 total times this season. They've finished 34-26 in those games.
• Milwaukee has a record of 25-23 when it has played as a moneyline underdog with odds of +102 or longer (52.1%).
• The Brewers have had an over/under set by oddsmakers 161 times, and have combined with opponents to go over the total in 81 of those games (81-78-2).
• The Brewers are 89-72-0 against the spread this season.

Cubs Player Leaders

• Kyle Tucker leads Chicago in OBP (.377) this season, fueled by 133 hits. He has a .266 batting average and a slugging percentage of .464.
• Among all qualified hitters, he is 46th in batting average, his on-base percentage ranks seventh, and he is 44th in slugging.
• Nico Hoerner leads Chicago in slugging percentage (.394) thanks to 40 extra-base hits. He's batting .297 with an on-base percentage of .345.
• He is eighth in batting average, 46th in on-base percentage and 110th in slugging in the major leagues.
• Hoerner has picked up at least one hit in six games in a row. In his last 10 outings he is hitting .268 with a double, two home runs, a walk and three RBIs.
• Pete Crow-Armstrong has collected 146 base hits, an OBP of .287 and a slugging percentage of .481 this season.
• Seiya Suzuki has been key for Chicago with 140 hits, an OBP of .326 plus a slugging percentage of .478.

Brewers Player Leaders

• Brice Turang has an on-base percentage of .359 and a slugging percentage of .435. Both lead the Brewers. He's batting .288.
• Including all qualifying hitters in the majors, he ranks 16th in batting average, 20th in on-base percentage and 71st in slugging percentage.
• Christian Yelich is batting .264 with 21 doubles, 29 home runs and 64 walks. He's slugging .452 with an on-base percentage of .343.
• He ranks 51st in batting average, 49th in on-base percentage and 56th in slugging percentage in MLB.
• William Contreras is hitting .260 with 28 doubles, 17 home runs and 84 walks.
• Jackson Chourio has collected 148 hits to pace his team.

Cubs vs Brewers Head to Head

• 10/6/2025: 7-3 MIL (Favorite: Brewers, Spread: -1.5, Total: 7.5, Favorite Moneyline: -136, Underdog Moneyline: +116)
• 10/4/2025: 9-3 MIL (Favorite: Brewers, Spread: -1.5, Total: 7.5, Favorite Moneyline: -138, Underdog Moneyline: +118)
• 8/21/2025: 4-1 MIL (Favorite: Cubs, Spread: -1.5, Total: 6.5, Favorite Moneyline: -138, Underdog Moneyline: +118)
• 8/20/2025: 4-3 CHC (Favorite: Brewers, Spread: -1.5, Total: 6.5, Favorite Moneyline: -118, Underdog Moneyline: -100)
• 8/19/2025: 4-1 CHC (Favorite: Brewers, Spread: -1.5, Total: 6.5, Favorite Moneyline: -120, Underdog Moneyline: +102)
• 8/19/2025: 6-4 CHC (Favorite: Cubs, Spread: -1.5, Total: 6.5, Favorite Moneyline: -152, Underdog Moneyline: +128)
• 8/18/2025: 7-0 MIL (Favorite: Cubs, Spread: -1.5, Total: 8, Favorite Moneyline: -118, Underdog Moneyline: -100)
• 7/30/2025: 10-3 CHC (Favorite: Brewers, Spread: -1.5, Total: 7, Favorite Moneyline: -120, Underdog Moneyline: +102)
• 7/29/2025: 9-3 MIL (Favorite: Brewers, Spread: -1.5, Total: 8.5, Favorite Moneyline: -124, Underdog Moneyline: +106)
• 7/28/2025: 8-4 MIL (Favorite: Cubs, Spread: -1.5, Total: 8, Favorite Moneyline: -116, Underdog Moneyline: -102)

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