Colts vs Cardinals Prediction, Odds, Picks, Best Bets for NFL Week 6

The NFL slate on Sunday includes the Indianapolis Colts taking on the Arizona Cardinals.
Before you place your bet on this matchup at FanDuel Sportsbook, here are the NFL moneyline insights you need to know.
Colts vs Cardinals Prediction & Pick
All NFL win probability predictions and picks are according to numberFire.
Prediction: Colts win (82.4%)
Colts vs Cardinals Point Spread
The Colts are 9.5-point favorites against the Cardinals. The Colts are -115 to cover the spread, while the Cardinals are -105 to cover as a 9.5-point underdog.
Colts vs Cardinals Over/Under
Colts versus Cardinals, on Oct. 12, has an over/under of 46.5, with the over being -105 and the under -115.
Colts vs Cardinals Moneyline
Looking at the moneyline for Cardinals-Colts, Arizona is the underdog at +385, and Indianapolis is -500 playing at home.
Colts vs Cardinals Betting Trends
- Indianapolis' record against the spread is 4-1-0.
- Indianapolis has had two games (out of five) go over the total this year.
- The Cardinals have won twice against the spread this year.
- Two Cardinals games (out of five) have hit the over this year.
Check out even more in-depth Colts vs. Cardinals analysis on FanDuel Research.
Colts vs Cardinals Odds & Spread
- All NFL odds, betting lines and prop bets are available on FanDuel Sportsbook.
- Moneyline: IND: (-500) | ARI: (+385)
- Spread: IND: -9.5 (-115) | ARI: +9.5 (-105)
- Total: 46.5 -- Over: (-105) | Under: (-115)
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