Colts vs Cardinals Prediction, Odds, Picks, Best Bets for NFL Week 6

The Indianapolis Colts versus the Arizona Cardinals is on the NFL schedule for Sunday.

All the information you need is below, in order to make a smart wager on this matchup at FanDuel Sportsbook.

Colts vs Cardinals Prediction & Pick

All NFL win probability predictions and picks are according to numberFire.
Prediction: Colts win (82.4%)

Colts vs Cardinals Point Spread

The Colts are 6.5-point favorites against the Cardinals. The Colts are -110 to cover the spread, while the Cardinals are -110 to cover as a 6.5-point underdog.

Colts vs Cardinals Over/Under

A combined point total of 47.5 has been set for Colts-Cardinals on Oct. 12, with the over at -105 and the under at -115.

Colts vs Cardinals Moneyline

Indianapolis is a -300 favorite on the moneyline, while Arizona is a +245 underdog on the road.

Colts vs Cardinals Betting Trends

• Indianapolis' record against the spread is 4-1-0.
• The Colts have covered every time (1-0) as a 6.5-point favorite or greater this season.
• Indianapolis has had two games (out of five) go over the total this season.
• The Cardinals have posted two wins against the spread this season.
• Two Cardinals games (out of five) have hit the over this year.

Check out even more in-depth Colts vs. Cardinals analysis on FanDuel Research.

Colts vs Cardinals Odds & Spread

• All NFL odds, betting lines and prop bets are available on FanDuel Sportsbook.
• Moneyline: IND: (-300) | ARI: (+245)
• Spread: IND: -6.5 (-110) | ARI: +6.5 (-110)
• Total: 47.5 -- Over: (-105) | Under: (-115)

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