Chiefs vs Titans Prediction, Odds, Picks, Best Bets for NFL Week 16

The Sunday slate in the NFL includes a matchup between the Kansas City Chiefs and the Tennessee Titans.

Before you place your bet on this matchup at FanDuel Sportsbook, here are the NFL moneyline insights you need to know.

Chiefs vs Titans Prediction & Pick

All NFL win probability predictions and picks are according to numberFire.
Prediction: Chiefs win (71.2%)

Chiefs vs Titans Point Spread

The Chiefs are 2.5-point favorites against the Titans. The Chiefs are -120 to cover the spread, while the Titans are -102 to cover as a 2.5-point underdog.

Chiefs vs Titans Over/Under

The over/under for the Chiefs versus Titans game on Dec. 21 has been set at 37.5, with -110 odds on the over and -110 odds on the under.

Chiefs vs Titans Moneyline

Tennessee is the underdog, +122 on the moneyline, while Kansas City is a -144 favorite despite being on the road.

Chiefs vs Titans Betting Trends

• Kansas City is 5-9-0 against the spread this season.
• The Chiefs have an ATS record of 4-8 as 2.5-point favorites or greater.
• Out of 14 Chiefs games so far this year, four have gone over the total.
• The Titans' record against the spread is 6-8-0.
• Tennessee's ATS record as 2.5-point underdogs or more is 6-8.
• Out of 14 Titans games so far this season, nine have gone over the total.

Check out even more in-depth Chiefs vs. Titans analysis on FanDuel Research.

Chiefs vs Titans Odds & Spread

• All NFL odds, betting lines and prop bets are available on FanDuel Sportsbook.
• Moneyline: KC: (-144) | TEN: (+122)
• Spread: KC: -2.5 (-120) | TEN: +2.5 (-102)
• Total: 37.5 -- Over: (-110) | Under: (-110)

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