Cavaliers vs. Lakers Prediction, Odds, Picks, Best Bets for Jan. 28

Cavaliers vs. Lakers Game Info

• Date: Wednesday, January 28, 2026
• Time: 7 p.m. ET
• Venue: Rocket Arena -- Cleveland, Ohio
• Coverage: ESPN and SportsNet LA

A pair of the league's best scorers square off when Donovan Mitchell (fifth, 29.5 PPG) and the Cleveland Cavaliers (28-20) host Luka Doncic (first, 33.8 PPG) and the Los Angeles Lakers (28-17) on Wednesday, January 28, 2026 at 7 p.m. ET on ESPN and SportsNet LA. The Cavaliers are 2.5-point favorites. The matchup has an over/under of 235.5.

Cavaliers vs. Lakers Odds & Spread

All NBA betting lines, odds and prop bets are from FanDuel Sportsbook.

Cavaliers vs. Lakers Prediction & Pick

All NBA win probability predictions and picks are according to numberFire.
Prediction: Cavaliers win (67.9%)

Cavaliers vs. Lakers Betting Trends

• The Cavaliers have put together a 19-29-0 record against the spread this season.
• The Lakers have played 45 games, with 24 wins against the spread.
• This season, Cavaliers games have hit the over 22 times out of 45 chances.
• Lakers games this season have hit the over 57.8% of the time (26 out of 45 games with a set point total).
• Cleveland has a worse record against the spread at home (9-18-0) than it does in road games (10-11-0).
• The Cavaliers have gone over the total in 11 of 27 home games (40.7%). They've done better in road games, eclipsing the total in 11 of 21 matchups (52.4%).
• Los Angeles has performed better against the spread away (14-11-0) than at home (10-9-1) this year.
• Looking at the over/under, Lakers games have finished over 15 of 20 times at home (75%), and 11 of 25 away (44%).

Cavaliers Leaders

• Mitchell's numbers on the season are 29.5 points, 4.8 rebounds and 5.8 assists per game, shooting 48.5% from the floor and 38.5% from downtown, with an average of 3.8 made 3-pointers (second in league).
• Jaylon Tyson averages 13.7 points, 5.6 rebounds and 2.3 assists, shooting 51.3% from the field and 46.6% from downtown (third in NBA), with 2 made 3-pointers per game.
• Jarrett Allen is averaging 13.3 points, 7.8 boards and 1.9 assists. At the other end, he averages 1 steal and 0.8 blocked shots.
• De'Andre Hunter's numbers on the season are 13.8 points, 4.3 rebounds and 2.1 assists per contest, shooting 42% from the floor and 30.6% from downtown, with an average of 1.7 made 3-pointers.
• Craig Porter Jr. is averaging 4.8 points, 3.6 rebounds and 3 assists. Defensively, he averages 0.9 steals and 0.6 blocked shots.

Lakers Leaders

• Doncic averages 33.8 points, 7.8 boards and 8.8 assists. He is also draining 47.1% of his shots from the floor and 34.3% from 3-point range, with 3.5 triples per game (fourth in league).
• The Lakers get 22.4 points per game from LeBron James, plus 6 rebounds and 6.7 assists.
• Deandre Ayton's numbers on the season are 13.4 points, 8.6 rebounds and 0.8 assists per contest. He is making 66% of his shots from the floor (second in NBA).
• Jake LaRavia's numbers on the season are 9.5 points, 4.3 boards and 2 assists per contest. He is draining 46.4% of his shots from the field and 34.8% from 3-point range, with an average of 1.2 triples.
• Marcus Smart averages 10.1 points, 3.1 rebounds and 2.8 assists. He is sinking 40.8% of his shots from the floor and 32.8% from beyond the arc, with 1.6 triples per game.

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