Canadiens vs Flames NHL Prediction, Odds, Picks, Best Bets for Oct. 22

The Montreal Canadiens are among the NHL teams busy on Wednesday, versus the Calgary Flames.

Before you make your wager on FanDuel Sportsbook, we've got you covered with all the latest NHL betting insights.

Canadiens vs Flames Game Info

• Montreal Canadiens (5-2) vs. Calgary Flames (1-6)
• Date: Wednesday, October 22, 2025
• Time: 8:30 p.m. ET
• Venue: Scotiabank Saddledome -- Calgary, Alberta
• Coverage: ESPN+

Canadiens vs Flames Odds

All NHL odds, betting lines and prop bets are available on FanDuel Sportsbook.

Canadiens vs Flames Prediction & Pick

All NHL win probability predictions and picks are according to numberFire.

• Prediction: Canadiens win (50.4%)

Canadiens vs Flames Puck Line

• The Flames are underdogs by 1.5 goals. The Flames are -265 to cover the spread, and the Canadiens are +210.

Canadiens vs Flames Over/Under

• The Canadiens-Flames matchup on Oct. 22 has been given an over/under of 5.5 goals. The over is -124 and the under is +102.

Canadiens vs Flames Moneyline

• Looking at the moneyline for Canadiens-Flames, Montreal is the favorite at -115, and Calgary is -104 playing at home.

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