Buccaneers vs 49ers Prediction, Odds, Picks, Best Bets for NFL Week 6

The NFL slate on Sunday includes the Tampa Bay Buccaneers taking on the San Francisco 49ers.

Get the latest NFL odds ahead of this game on FanDuel Sportsbook.

Buccaneers vs 49ers Prediction & Pick

All NFL win probability predictions and picks are according to numberFire.
Prediction:

Buccaneers vs 49ers Point Spread

The Buccaneers are 3.5-point favorites against the 49ers. The Buccaneers are -102 to cover the spread, while the 49ers are -120 to cover as a 3.5-point underdog.

Buccaneers vs 49ers Over/Under

The Buccaneers-49ers game on Oct. 12 has been given an over/under of 46.5 points. The over is -118 and the under is -104.

Buccaneers vs 49ers Moneyline

The moneyline numbers for Buccaneers vs. 49ers reveal Tampa Bay as the favorite (-186) and San Francisco as the underdog (+156) on the road.

Buccaneers vs 49ers Betting Trends

• Against the spread, Tampa Bay is 3-2-0 this year.
• The Buccaneers have no wins ATS (0-1) as a 3.5-point favorite or greater this season.
• The Buccaneers have seen three of their five games go over the point total.
• The 49ers have three wins in five contests against the spread this season.
• San Francisco is unbeaten ATS (1-0) as a 3.5-point underdog or more this season.
• The 49ers have seen three of their five games go over the point total.

Check out even more in-depth Buccaneers vs. 49ers analysis on FanDuel Research.

Buccaneers vs 49ers Odds & Spread

• All NFL odds, betting lines and prop bets are available on FanDuel Sportsbook.
• Moneyline: TB: (-186) | SF: (+156)
• Spread: TB: -3.5 (-102) | SF: +3.5 (-120)
• Total: 46.5 -- Over: (-118) | Under: (-104)

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