Brewers vs Cubs Prediction, Odds, Moneyline, Spread & Over/Under for NLDS Game 5 on Oct. 11

Odds updated as of 7:12 p.m.

The MLB slate on Saturday includes the Milwaukee Brewers facing the Chicago Cubs in Game 5 of the NLDS.

Before you do any MLB betting on this matchup at FanDuel Sportsbook, here's what you need to know.

Brewers vs Cubs Game Info

• Milwaukee Brewers (97-65) vs. Chicago Cubs (92-70)
• Date: Saturday, October 11, 2025
• Time: 8:08 p.m. ET
• Venue: American Family Field -- Milwaukee, Wisconsin
• Coverage: truTV, TBS, and HBO Max

Brewers vs Cubs Odds & Moneyline

• All MLB odds, betting lines and prop bets are available on FanDuel Sportsbook.
• Moneyline: MIL: (-142) | CHC: (+120)
• Spread: MIL: -1.5 (+136) | CHC: +1.5 (-164)
• Total: 7.5 -- Over: (-110) | Under: (-110)

Brewers vs Cubs Probable Starting Pitchers

Probable Pitchers: Trevor Megill (Brewers) - 6-3, 2.49 ERA vs Drew Pomeranz (Cubs) - 2-2, 2.17 ERA

The Brewers will give the nod to Trevor Megill (6-3, 2.49 ERA) against the Cubs and Drew Pomeranz (2-2, 2.17 ERA). Megill did not pitch in a game with a spread last season. Megill did not appear in a game when his team was the moneyline favorite last season. When Pomeranz starts, the Cubs have gone 2-2-0 against the spread. The Cubs have not been a moneyline underdog when Pomeranz starts this season.

Brewers vs Cubs Prediction & Pick

All MLB win probability predictions and picks are according to numberFire.
Prediction: Brewers win (52.8%)

Brewers vs Cubs Moneyline

• Looking at the moneyline for Cubs-Brewers, Chicago is the underdog at +120, and Milwaukee is -142 playing at home.

Brewers vs Cubs Spread

• The Brewers are hosting the Cubs and are favored by 1.5 runs on the spread. The Brewers are +136 to cover the runline, with the Cubs being -164.

Brewers vs Cubs Over/Under

• An over/under of 7.5 has been set for Brewers-Cubs on Oct. 11, with the over being -110 and the under -110.

Bet on Milwaukee Brewers vs. Chicago Cubs on FanDuel today!

Brewers vs Cubs Betting Trends

• The Brewers have been favorites in 99 games this season and have come away with the win 62 times (62.6%) in those contests.
• This season Milwaukee has been victorious 35 times in 48 chances when named as a favorite of at least -142 on the moneyline.
• The Brewers and their opponents have hit the over in 82 of their 163 games with a total set by oddsmakers this season.
• The Brewers have an against the spread mark of 89-74-0 in 163 games with a line this season.
• The Cubs have won 40.4% of the games this season they were the moneyline underdog (19-28).
• In games it has played as a moneyline underdog with odds of +120 or longer, Chicago has a 5-6 record (winning 45.5% of its games).
• The Cubs have played in 164 games with an over/under set, and have combined with opponents to go over the total 77 times (77-76-11).
• The Cubs have covered 48.2% of their games this season, going 79-85-0 against the spread.

Brewers Player Leaders

• Brice Turang leads Milwaukee OPS (.794) this season. He has a .288 batting average, an on-base percentage of .359, and a slugging percentage of .435.
• Among all qualifying hitters in the majors, his batting average ranks 16th, his on-base percentage ranks 20th, and he is 71st in slugging.
• Christian Yelich is batting .264 with 21 doubles, 29 home runs and 64 walks, while slugging .452 with an on-base percentage of .343.
• His batting average is 51st among qualified players, his on-base percentage 49th, and his slugging percentage 56th.
• William Contreras has collected 147 base hits, an OBP of .355 and a slugging percentage of .399 this season.
• Jackson Chourio has 148 hits, which leads Milwaukee hitters this season, while batting .270 with 60 extra-base hits.
• Chourio enters this matchup on a six-game hitting streak. In his last 10 games he is batting .268 with three doubles, two home runs, two walks and seven RBIs.

Cubs Player Leaders

• Kyle Tucker a has .377 on-base percentage to lead the Cubs. He's batting .266 while slugging .464.
• Including all qualifying hitters in the big leagues, he ranks 46th in batting average, seventh in on-base percentage and 44th in slugging percentage.
• Nico Hoerner paces his team with a .394 slugging percentage. He has a batting average of .297 with an on-base percentage of .345.
• His batting average is eighth among all qualified players, his on-base percentage ranks 46th, and he is 110th in slugging.
• Pete Crow-Armstrong is batting .247 with 37 doubles, four triples, 31 home runs and 29 walks.
• Michael Busch's 137 hits pace his team.

Brewers vs Cubs Head to Head

• 10/9/2025: 6-0 CHC (Favorite: Brewers, Spread: -1.5, Total: 7, Favorite Moneyline: -118, Underdog Moneyline: -100)
• 10/8/2025: 4-3 CHC (Favorite: Cubs, Spread: -1.5, Total: 6.5, Favorite Moneyline: -108, Underdog Moneyline: -108)
• 10/6/2025: 7-3 MIL (Favorite: Brewers, Spread: -1.5, Total: 7.5, Favorite Moneyline: -136, Underdog Moneyline: +116)
• 10/4/2025: 9-3 MIL (Favorite: Brewers, Spread: -1.5, Total: 7.5, Favorite Moneyline: -138, Underdog Moneyline: +118)
• 8/21/2025: 4-1 MIL (Favorite: Cubs, Spread: -1.5, Total: 6.5, Favorite Moneyline: -138, Underdog Moneyline: +118)
• 8/20/2025: 4-3 CHC (Favorite: Brewers, Spread: -1.5, Total: 6.5, Favorite Moneyline: -118, Underdog Moneyline: -100)
• 8/19/2025: 4-1 CHC (Favorite: Brewers, Spread: -1.5, Total: 6.5, Favorite Moneyline: -120, Underdog Moneyline: +102)
• 8/19/2025: 6-4 CHC (Favorite: Cubs, Spread: -1.5, Total: 6.5, Favorite Moneyline: -152, Underdog Moneyline: +128)
• 8/18/2025: 7-0 MIL (Favorite: Cubs, Spread: -1.5, Total: 8, Favorite Moneyline: -118, Underdog Moneyline: -100)
• 7/30/2025: 10-3 CHC (Favorite: Brewers, Spread: -1.5, Total: 7, Favorite Moneyline: -120, Underdog Moneyline: +102)

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