Brewers vs Cubs Prediction, Odds, Moneyline, Spread & Over/Under for NLDS Game 1 on Oct. 4

Odds updated as of 9:12 p.m.

In MLB action on Saturday, the Milwaukee Brewers take on the Chicago Cubs in Game 1 of the NLDS.

Before you do any MLB betting on this game at FanDuel Sportsbook, here's everything you need to know.

Brewers vs Cubs Game Info

• Milwaukee Brewers (97-65) vs. Chicago Cubs (92-70)
• Date: Saturday, October 4, 2025
• Time: 2:08 p.m. ET
• Venue: American Family Field -- Milwaukee, Wisconsin
• Coverage: TBS and HBO Max

Brewers vs Cubs Odds & Moneyline

• All MLB odds, betting lines and prop bets are available on FanDuel Sportsbook.
• Moneyline: MIL: (-156) | CHC: (+132)
• Spread: MIL: -1.5 (+142) | CHC: +1.5 (-172)
• Total: 7.5 -- Over: (-100) | Under: (-122)

Brewers vs Cubs Probable Starting Pitchers

Probable Pitchers: Freddy Peralta (Brewers) - 17-6, 2.70 ERA vs Matthew Boyd (Cubs) - 14-8, 3.21 ERA

The probable pitchers are Freddy Peralta (17-6, 2.70 ERA) for the Brewers and Matthew Boyd (14-8, 3.21 ERA) for the Cubs. Peralta's team is 19-14-0 against the spread in his starts this season. Peralta's team is 14-8 this season when he starts and they are the moneyline favorite. The Cubs have a 14-17-0 ATS record in Boyd's 31 starts that had a set spread. The Cubs have a 1-4 record in Boyd's five starts this season when they were the moneyline underdog.

Brewers vs Cubs Prediction & Pick

All MLB win probability predictions and picks are according to numberFire.
Prediction: Brewers win (60.5%)

Brewers vs Cubs Moneyline

• The moneyline numbers for Brewers vs. Cubs reveal Milwaukee as the favorite (-156) and Chicago as the underdog (+132) on the road.

Brewers vs Cubs Spread

• The Cubs are +1.5 on the run line against the Brewers. The Cubs are -172 to cover, and the Brewers are +142.

Brewers vs Cubs Over/Under

• The over/under for Brewers-Cubs on Oct. 4 is 7.5. The over is -100, and the under is -122.

Bet on Milwaukee Brewers vs. Chicago Cubs on FanDuel today!

Brewers vs Cubs Betting Trends

• The Brewers have been victorious in 60, or 62.5%, of the 96 contests they have been chosen as favorites in this season.
• This season Milwaukee has been victorious 22 times in 30 chances when named as a favorite of at least -156 on the moneyline.
• The Brewers and their opponents have gone over in 79 of their 159 games with a total set by sportsbooks this season.
• The Brewers have an against the spread record of 87-72-0 in 159 games with a line this season.
• The Cubs have won 40.9% of the games this season they were the moneyline underdog (18-26).
• Chicago has a 4-3 record (winning 57.1% of its games) when it has played as a moneyline underdog of +132 or longer.
• The Cubs have played in 160 games with an over/under set, and have combined with their opponents to go over the total 74 times (74-75-11).
• The Cubs have covered 48.1% of their games this season, going 77-83-0 against the spread.

Brewers Player Leaders

• Brice Turang leads Milwaukee OPS (.794) this season. He has a .288 batting average, an on-base percentage of .359, and a slugging percentage of .435.
• Among qualified hitters in baseball, his batting average ranks 16th, his on-base percentage ranks 20th, and he is 71st in slugging.
• Turang has hit safely in four games in a row. In his last five games he is hitting .353 with two doubles, four walks and four RBIs.
• Christian Yelich is hitting .264 with 21 doubles, 29 home runs and 64 walks, while slugging .452 with an on-base percentage of .343.
• Among qualified batters, he ranks 51st in batting average, 49th in on-base percentage and 56th in slugging percentage.
• William Contreras has collected 147 base hits, an OBP of .355 and a slugging percentage of .399 this season.
• Jackson Chourio leads Milwaukee in total hits (148) this season while batting .270 with 60 extra-base hits.
• Chourio brings a two-game hitting streak into this matchup. In his last five games he is hitting .200 with a double, a home run, two walks and an RBI.

Cubs Player Leaders

• Kyle Tucker a has .377 on-base percentage to pace the Cubs. He's batting .266 while slugging .464.
• He ranks 46th in batting average, seventh in on-base percentage and 44th in slugging percentage among all qualifying hitters in MLB.
• Nico Hoerner's .394 slugging percentage leads his team. He has a batting average of .297 with an on-base percentage of .345.
• He is currently eighth in batting average, 46th in on-base percentage and 110th in slugging percentage among all qualified hitters.
• Pete Crow-Armstrong is batting .247 with 37 doubles, four triples, 31 home runs and 29 walks.
• Michael Busch's 137 hits pace his team.

Brewers vs Cubs Head to Head

• 8/21/2025: 4-1 MIL (Favorite: Cubs, Spread: -1.5, Total: 6.5, Favorite Moneyline: -138, Underdog Moneyline: +118)
• 8/20/2025: 4-3 CHC (Favorite: Brewers, Spread: -1.5, Total: 6.5, Favorite Moneyline: -118, Underdog Moneyline: -100)
• 8/19/2025: 4-1 CHC (Favorite: Brewers, Spread: -1.5, Total: 6.5, Favorite Moneyline: -120, Underdog Moneyline: +102)
• 8/19/2025: 6-4 CHC (Favorite: Cubs, Spread: -1.5, Total: 6.5, Favorite Moneyline: -152, Underdog Moneyline: +128)
• 8/18/2025: 7-0 MIL (Favorite: Cubs, Spread: -1.5, Total: 8, Favorite Moneyline: -118, Underdog Moneyline: -100)
• 7/30/2025: 10-3 CHC (Favorite: Brewers, Spread: -1.5, Total: 7, Favorite Moneyline: -120, Underdog Moneyline: +102)
• 7/29/2025: 9-3 MIL (Favorite: Brewers, Spread: -1.5, Total: 8.5, Favorite Moneyline: -124, Underdog Moneyline: +106)
• 7/28/2025: 8-4 MIL (Favorite: Cubs, Spread: -1.5, Total: 8, Favorite Moneyline: -116, Underdog Moneyline: -102)
• 6/19/2025: 8-7 MIL (Favorite: Cubs, Spread: -1.5, Total: 8.5, Favorite Moneyline: -126, Underdog Moneyline: +108)
• 6/17/2025: 5-3 CHC (Favorite: Cubs, Spread: -1.5, Total: 9.5, Favorite Moneyline: -156, Underdog Moneyline: +132)

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