Blue Jays vs Guardians Prediction, Odds, Moneyline, Spread & Over/Under for Sept. 2

Odds updated as of 6:12 p.m.

The Toronto Blue Jays versus the Cleveland Guardians is on the MLB schedule for Wednesday.

Before checking out the MLB betting lines on FanDuel Sportsbook, we've got you covered, in terms of the vital info regarding this matchup.

Blue Jays vs Guardians Game Info

• Toronto Blue Jays (68-71) vs. Cleveland Guardians (70-68)
• Date: Wednesday, September 2, 2026
• Time: 6:40 p.m. ET
• Venue: Progressive Field -- Cleveland, Ohio
• Coverage: CleGuardians.TV and SNET

Blue Jays vs Guardians Odds & Moneyline

• All MLB odds, betting lines and prop bets are available on FanDuel Sportsbook.
• Moneyline: TOR: (-132) | CLE: (+112)
• Spread: TOR: -1.5 (+134) | CLE: +1.5 (-162)
• Total: 7.5 -- Over: (+100) | Under: (-122)

Blue Jays vs Guardians Probable Starting Pitchers

Probable Pitchers: Dylan Cease (Blue Jays) - 9-5, 2.33 ERA vs Joey Cantillo (Guardians) - 9-7, 3.70 ERA

The Blue Jays will give the nod to Dylan Cease (9-5, 2.33 ERA), who is eyeing win No. 10 on the season, and the Guardians will turn to Joey Cantillo (9-7, 3.70 ERA). Cease and his team have a record of 15-10-0 against the spread when he starts. Cease's team has a record of 13-8 this season when he starts and they are the favorite on the moneyline. The Guardians have a 17-11-0 ATS record in Cantillo's 28 starts with a set spread. The Guardians have a 9-4 record in Cantillo's 13 starts this season when they were the moneyline underdog.

Blue Jays vs Guardians Prediction & Pick

All MLB win probability predictions and picks are according to numberFire.
Prediction: Guardians win (51.2%)

Blue Jays vs Guardians Moneyline

• Toronto is the favorite, -132 on the moneyline, while Cleveland is a +112 underdog despite being at home.

Blue Jays vs Guardians Spread

• The Guardians are +1.5 on the spread (-162 to cover), and Toronto is +134 to cover the runline.

Blue Jays vs Guardians Over/Under

• Blue Jays versus Guardians on Sept. 2 has an over/under of 7.5 runs, with the odds on the over +100 and the under set at -122.

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Blue Jays vs Guardians Betting Trends

• The Blue Jays have come away with 36 wins in the 66 contests they have been listed as the favorites in this season.
• This season Toronto has come away with a win 20 times in 36 chances when named as a favorite of at least -132 on the moneyline.
• The Blue Jays and their opponents have gone over in 68 of their 135 games with a total set by sportsbooks this season.
• The Blue Jays have posted a record of 66-69-0 against the spread this season.
• The Guardians have won 26 of the 51 games they were listed as the moneyline underdog this season (51%).
• In games it has played as a moneyline underdog with odds of +112 or longer, Cleveland has an 18-11 record (winning 62.1% of its games).
• The Guardians have played in 132 games with an over/under set, and have combined with opponents to go over the total 63 times (63-69-0).
• The Guardians have put together a 64-68-0 record ATS this season (covering 48.5% of the time).

Blue Jays Player Leaders

• Ernie Clement leads Toronto in slugging percentage (.389) thanks to 39 extra-base hits. He has a .275 batting average and an on-base percentage of .301.
• Among all qualified hitters in MLB, he is 33rd in batting average, 119th in on-base percentage, and 103rd in slugging.
• Vladimir Guerrero Jr. leads Toronto with an OBP of .330 this season while batting .258 with 49 walks and 63 runs scored. He's slugging .348.
• Among qualifying batters, he ranks 62nd in batting average, 73rd in on-base percentage and 133rd in slugging percentage.
• Guerrero brings a two-game streak with at least one hit into this contest. In his last five games he is batting .158 with a double, two walks and two RBIs.
• Kazuma Okamoto leads Toronto with 112 hits. He is batting .229 this season and 49 of his hits have gone for extra bases.
• Okamoto has recorded at least one base hit in two games in a row. During his last five outings he is batting .267 with a double, two home runs, three walks and four RBIs.
• George Springer has 14 home runs, 45 RBI and a batting average of .251 this season.

Guardians Player Leaders

• Chase DeLauter has accumulated 125 hits with a .450 slugging percentage, both team-best numbers for the Guardians. He's batting .290 and with an on-base percentage of .362.
• He ranks 10th in batting average, 27th in on-base percentage and 44th in slugging percentage among all qualifying hitters in MLB.
• Jose Ramirez is hitting .244 with 24 doubles, 11 home runs and 56 walks. He's slugging .391 with an on-base percentage of .338.
• He ranks 93rd in batting average, 58th in on-base percentage and 100th in slugging percentage in the majors.
• Steven Kwan has racked up a team-best .376 on-base percentage.
• Brayan Rocchio has 19 doubles, two triples, 10 home runs and 32 walks while hitting .246.

Blue Jays vs Guardians Head to Head

• 9/1/2026: 6-1 CLE (Favorite: Guardians, Spread: -1.5, Total: 7.5, Favorite Moneyline: -184, Underdog Moneyline: +154)
• 4/26/2026: 4-2 TOR (Favorite: Blue Jays, Spread: -1.5, Total: 8.5, Favorite Moneyline: -130, Underdog Moneyline: +110)
• 4/25/2026: 5-3 TOR (Favorite: Blue Jays, Spread: -1.5, Total: 7, Favorite Moneyline: -156, Underdog Moneyline: +132)
• 4/24/2026: 8-6 CLE (Favorite: Guardians, Spread: -1.5, Total: 8, Favorite Moneyline: -124, Underdog Moneyline: +106)
• 6/26/2025: 6-0 TOR (Favorite: Guardians, Spread: -1.5, Total: 7.5, Favorite Moneyline: -136, Underdog Moneyline: +116)
• 6/25/2025: 5-4 CLE (Favorite: Guardians, Spread: -1.5, Total: 8.5, Favorite Moneyline: -120, Underdog Moneyline: +102)
• 6/24/2025: 10-6 TOR (Favorite: Blue Jays, Spread: -1.5, Total: 9, Favorite Moneyline: -132, Underdog Moneyline: +112)
• 5/4/2025: 5-4 CLE (Favorite: Guardians, Spread: -1.5, Total: 8.5, Favorite Moneyline: -112, Underdog Moneyline: -104)
• 5/3/2025: 5-3 CLE (Favorite: Blue Jays, Spread: -1.5, Total: 7.5, Favorite Moneyline: -156, Underdog Moneyline: +132)
• 5/2/2025: 5-3 TOR (Favorite: Blue Jays, Spread: -1.5, Total: 8.5, Favorite Moneyline: -172, Underdog Moneyline: +144)

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