Pirates vs Giants Prediction, Odds, Moneyline, Spread & Over/Under for Sept. 2

Odds updated as of 6:12 p.m.

MLB action on Wednesday includes the Pittsburgh Pirates facing the San Francisco Giants.

Before you do any MLB betting on this game at FanDuel Sportsbook, here's everything you need to know.

Pirates vs Giants Game Info

• Pittsburgh Pirates (68-71) vs. San Francisco Giants (57-82)
• Date: Wednesday, September 2, 2026
• Time: 6:40 p.m. ET
• Venue: PNC Park -- Pittsburgh, Pennsylvania
• Coverage: SportsNet PT and NBCS-BA

Pirates vs Giants Odds & Moneyline

• All MLB odds, betting lines and prop bets are available on FanDuel Sportsbook.
• Moneyline: PIT: (-152) | SF: (+128)
• Spread: PIT: -1.5 (+134) | SF: +1.5 (-162)
• Total: 8.5 -- Over: (-122) | Under: (+100)

Pirates vs Giants Probable Starting Pitchers

Probable Pitchers: Bubba Chandler (Pirates) - 6-9, 4.26 ERA vs Landen Roupp (Giants) - 8-13, 4.25 ERA

This contest's pitching matchup is set, as the Pirates will send Bubba Chandler (6-9) to the mound, while Landen Roupp (8-13) will get the nod for the Giants. Chandler's team is 14-11-0 against the spread this season in his starts. Chandler's team has won 44.4% of his starts when they are favored on the moneyline (4-5). The Giants are 8-18-0 against the spread when Roupp starts. The Giants have been the underdog on the moneyline in 18 of Roupp's starts this season, and they went 7-11 in those matchups.

Pirates vs Giants Prediction & Pick

All MLB win probability predictions and picks are according to numberFire.
Prediction: Pirates win (58.1%)

Pirates vs Giants Moneyline

• The Pirates vs Giants moneyline has Pittsburgh as a -152 favorite, while San Francisco is a +128 underdog on the road.

Pirates vs Giants Spread

• The Pirates are hosting the Giants and are favored by 1.5 runs on the spread. The Pirates are +134 to cover the runline, with the Giants being -162.

Pirates vs Giants Over/Under

• The over/under for the Pirates versus Giants game on Sept. 2 has been set at 8.5, with -122 odds on the over and +100 odds on the under.

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Pirates vs Giants Betting Trends

• The Pirates have come away with 40 wins in the 71 contests they have been listed as the favorites in this season.
• Pittsburgh has a record of 9-11 in contests when sportsbooks favor them by -152 or more on the moneyline.
• The Pirates' games have gone over the total in 74 of their 137 opportunities.
• The Pirates have posted a record of 66-71-0 against the spread this season.
• The Giants have gone 33-58 in games they were listed as the moneyline underdog (winning 36.3% of those games).
• San Francisco is 14-21 (winning 40% of its games) when playing as a moneyline underdog of +128 or longer.
• The Giants have played in 136 games with an over/under set, and have combined with their opponents to go over the total 65 times (65-62-9).
• The Giants have a 65-71-0 record against the spread this season.

Pirates Player Leaders

• Bryan Reynolds is batting .262 with 32 doubles, two triples, 15 home runs and 79 walks. He has an on-base percentage of .369 and a slugging percentage of .419.
• Among qualifying hitters in MLB, his batting average ranks 58th, his on-base percentage ranks 19th, and he is 71st in slugging.
• Reynolds will look for his fourth straight game with a hit in this matchup. In his last five games he is batting .238 with two walks.
• Brandon Lowe leads Pittsburgh in total hits (130) this season while batting .256 with 57 extra-base hits. He's slugging .484 with an on-base percentage of .323.
• He ranks 65th in batting average, 86th in on-base percentage and 26th in slugging among qualified hitters.
• Lowe heads into this game looking to extend his three-game hit streak. In his last five games he is batting .438 with a double, two home runs, four walks and three RBIs.
• Nick Gonzales is slashing .310/.371/.398 this season and leads the Pirates with an OPS of .770.
• Gonzales has recorded at least one base hit in three games in a row. In his last five games he is batting .368 with a double, three walks and two RBIs.
• Oneil Cruz has 17 home runs, 56 RBI and a batting average of .271 this season.
• Cruz has hit safely in four games in a row. In his last five games he is hitting .409 with a double, two walks and four RBIs.

Giants Player Leaders

• Rafael Devers has accumulated 132 hits with a .332 on-base percentage, leading the Giants in both categories. He's batting .252 and slugging .494.
• Including all the qualified hitters in the big leagues, his batting average ranks 77th, his on-base percentage is 70th, and he is 19th in slugging.
• Devers hopes to build on a nine-game hitting streak in this matchup. In his last 10 outings he is batting .368 with a double, five home runs, seven walks and 12 RBIs.
• Jung Hoo Lee is slugging .415 to pace his team. He has a batting average of .285 with an on-base percentage of .329.
• Including all qualifying hitters, his batting average puts him 16th, his on-base percentage ranks 75th, and he is 79th in slugging.
• Bryce Eldridge is batting .263 with 17 doubles, 15 home runs and 49 walks.
• Drew Gilbert has 13 doubles, three triples, eight home runs and 33 walks while hitting .236.

Pirates vs Giants Head to Head

• 9/1/2026: 13-12 PIT (Favorite: Pirates, Spread: -1.5, Total: 7.5, Favorite Moneyline: -172, Underdog Moneyline: +144)
• 5/10/2026: 7-6 SF (Favorite: Giants, Spread: -1.5, Total: 8, Favorite Moneyline: -124, Underdog Moneyline: +106)
• 5/9/2026: 13-3 PIT (Favorite: Pirates, Spread: -1.5, Total: 7, Favorite Moneyline: -110, Underdog Moneyline: -106)
• 5/8/2026: 5-2 SF (Favorite: Giants, Spread: -1.5, Total: 7.5, Favorite Moneyline: -108, Underdog Moneyline: -108)
• 8/6/2025: 4-2 SF (Favorite: Giants, Spread: -1.5, Total: 8, Favorite Moneyline: -154, Underdog Moneyline: +130)
• 8/5/2025: 8-1 SF (Favorite: Giants, Spread: -1.5, Total: 7.5, Favorite Moneyline: -144, Underdog Moneyline: +122)
• 8/4/2025: 5-4 PIT (Favorite: Giants, Spread: -1.5, Total: 8.5, Favorite Moneyline: -126, Underdog Moneyline: +108)
• 7/30/2025: 2-1 PIT (Favorite: Giants, Spread: -1.5, Total: 7, Favorite Moneyline: -210, Underdog Moneyline: +176)
• 7/29/2025: 3-1 PIT (Favorite: Giants, Spread: -1.5, Total: 8, Favorite Moneyline: -174, Underdog Moneyline: +146)
• 7/28/2025: 6-5 PIT (Favorite: Giants, Spread: -1.5, Total: 7.5, Favorite Moneyline: -136, Underdog Moneyline: +116)

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