Bills vs Panthers Prediction, Odds, Picks, Best Bets for NFL Week 8

The NFL's Sunday slate includes the Buffalo Bills facing the Carolina Panthers.

Get the latest NFL odds ahead of this game on FanDuel Sportsbook.

Bills vs Panthers Prediction & Pick

All NFL win probability predictions and picks are according to numberFire.
Prediction: Bills win (62.6%)

Bills vs Panthers Point Spread

The Bills are 7.5-point favorites against the Panthers. The Bills are -102 to cover the spread, while the Panthers are -120 to cover as a 7.5-point underdog.

Bills vs Panthers Over/Under

The Bills-Panthers matchup on Oct. 26 has been given an over/under of 46.5 points. The over is -105 and the under is -115.

Bills vs Panthers Moneyline

Buffalo is the favorite, -370 on the moneyline, while Carolina is a +295 underdog despite being at home.

Bills vs Panthers Betting Trends

• Buffalo has won twice against the spread this year.
• The Bills have no wins ATS (0-3) as a 7.5-point favorite or greater this season.
• There have been three Bills games (out of six) that hit the over this year.
• The Panthers have five wins in seven contests against the spread this year.
• This year, four of the Panthers' seven games have gone over the point total.

Check out even more in-depth Bills vs. Panthers analysis on FanDuel Research.

Bills vs Panthers Odds & Spread

• All NFL odds, betting lines and prop bets are available on FanDuel Sportsbook.
• Moneyline: BUF: (-370) | CAR: (+295)
• Spread: BUF: -7.5 (-102) | CAR: +7.5 (-120)
• Total: 46.5 -- Over: (-105) | Under: (-115)

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