Odds updated as of 1:11 PM

The MLB's Wednesday slate includes the Houston Astros taking on the St. Louis Cardinals.

Before you do any MLB betting on this game at FanDuel Sportsbook, here's everything you need to know.

Astros vs Cardinals Game Info

• Houston Astros (28-34) vs. St. Louis Cardinals (28-31)
• Date: Wednesday, June 5, 2024
• Time: 2:10 PM ET
• Venue: Minute Maid Park -- Houston, Texas
• Coverage: SCHN

Astros vs Cardinals Odds & Moneyline

• All MLB odds, betting lines and prop bets are available on FanDuel Sportsbook.
• Moneyline: HOU: (-158) | STL: (+134)
• Spread: HOU: -1.5 (+134) | STL: +1.5 (-162)
• Total: 9 -- Over: (-100) | Under: (-122)

Astros vs Cardinals Probable Starting Pitchers

Probable Pitchers: Ronel Blanco (Astros) - 5-1, 2.44 ERA vs Miles Mikolas (Cardinals) - 3-6, 5.54 ERA

The probable pitchers are Ronel Blanco (5-1) for the Astros and Miles Mikolas (3-6) for the Cardinals. Blanco and his team are 7-3-0 ATS this season when he starts. Blanco's team has a record of 6-2 this season when he starts and they are the favorite on the moneyline. The Cardinals have a 5-7-0 ATS record in Mikolas' 12 starts with a set spread. The Cardinals are 4-3 in Mikolas' seven starts this season that they were the underdog on the moneyline.

Astros vs Cardinals Prediction & Pick

All MLB win probability predictions and picks are according to numberFire.
Prediction: Astros win (56.7%)

Astros vs Cardinals Moneyline

• Houston is a -158 favorite on the moneyline, while St. Louis is a +134 underdog on the road.

Astros vs Cardinals Spread

• The Cardinals are +1.5 on the spread (-162 to cover), and Houston is +134 to cover the runline.

Astros vs Cardinals Over/Under

• An over/under of 9 has been set for Astros-Cardinals on June 5, with the over being -100 and the under -122.

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Astros vs Cardinals Betting Trends

• The Astros have been victorious in 22, or 46.8%, of the 47 contests they have been chosen as favorites in this season.
• This year Houston has won 12 of 19 games when listed as at least -158 on the moneyline.
• The Astros and their opponents have hit the over in 23 of their 62 games with a total set by oddsmakers this season.
• The Astros are 27-35-0 against the spread in their 62 games that had a posted line this season.
• The Cardinals are 12-18 in games they were the underdog on the moneyline (winning 40% of those games).
• In games it has played as a moneyline underdog with odds of +134 or longer, St. Louis has a 1-7 record (winning only 12.5% of its games).
• In the 56 games bookmakers have set an over/under for the Cardinals, they have combined with opponents to go over the total 25 times (25-29-2).
• The Cardinals have put together a 26-30-0 record ATS this season (covering 46.4% of the time).

Astros Player Leaders

• Kyle Tucker leads Houston with 57 hits and an OBP of .395 this season. He has a .266 batting average and a slugging percentage of .584.
• Among qualified batters in baseball, his batting average ranks 49th, his on-base percentage ranks sixth, and he is sixth in slugging.
• Tucker hopes to build on a three-game hitting streak in this matchup. In his last five games he is hitting .267 with a home run, two walks and an RBI.
• Yordan Alvarez is hitting .289 with 12 doubles, 12 home runs and 25 walks. He's slugging .494 with an on-base percentage of .362.
• He is 23rd in batting average, 23rd in on-base percentage and 22nd in slugging among qualifying hitters.
• Alvarez has picked up at least one hit in eight straight games. In his last 10 outings he is batting .385 with two doubles, three home runs, three walks and six RBI.
• Jose Altuve leads Houston in slugging percentage (.446) powered by 21 extra-base hits.
• Altuve enters this game with two games in a row with at least one hit. During his last five outings he is hitting .278 with a double, a walk and an RBI.
• Jeremy Pena has been key for Houston with 71 hits, an OBP of .336 plus a slugging percentage of .417.
• Pena takes a two-game hitting streak into this game. In his last five games he is hitting .235 with a double, a walk and two RBI.

Cardinals Player Leaders

• Brendan Donovan is batting .236 with 14 doubles, a triple, four home runs and 19 walks. He's slugging .368 with an on-base percentage of .318.
• Including all qualifying hitters in the big leagues, he is 101st in batting average, 81st in on-base percentage and 116th in slugging percentage.
• Masyn Winn has a .359 on-base percentage to pace his team. He has a batting average of .309 while slugging .446.
• He ranks 10th in batting average, 25th in on-base percentage and 48th in slugging percentage in MLB.
• Nolan Arenado has a team-high .363 slugging percentage.
• Nolan Gorman's 43 hits pace his team.

Astros vs Cardinals Head to Head

• 6/4/2024: 8-5 HOU (Favorite: Astros, Spread: -1.5, Total: 9, Favorite Moneyline: -158, Underdog Moneyline: +134)
• 6/3/2024: 7-4 HOU (Favorite: Astros, Spread: -1.5, Total: 8, Favorite Moneyline: -180, Underdog Moneyline: +152)
• 6/29/2023: 14-0 HOU (Favorite: Astros, Spread: -1.5, Total: 10, Favorite Moneyline: -120, Underdog Moneyline: +102)
• 6/28/2023: 10-7 HOU (Favorite: Cardinals, Spread: -1.5, Total: 9, Favorite Moneyline: -126, Underdog Moneyline: +108)
• 6/27/2023: 4-2 STL (Favorite: Astros, Spread: -1.5, Total: 7.5, Favorite Moneyline: -112, Underdog Moneyline: -104)

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