Astros vs Angels Prediction, Odds, Moneyline, Spread & Over/Under for Sept. 22

Odds updated as of 1:11 p.m.

The MLB's Sunday slate includes the Houston Astros facing the Los Angeles Angels.

Here's what you need to know before checking out today's MLB odds and spreads on FanDuel Sportsbook.

Astros vs Angels Game Info

• Houston Astros (85-70) vs. Los Angeles Angels (62-93)
• Date: Sunday, September 22, 2024
• Time: 2:10 p.m. ET
• Venue: Minute Maid Park -- Houston, Texas
• Coverage: BSW

Astros vs Angels Odds & Moneyline

• All MLB odds, betting lines and prop bets are available on FanDuel Sportsbook.
• Moneyline: HOU: (-275) | LAA: (+225)
• Spread: HOU: -1.5 (-128) | LAA: +1.5 (+106)
• Total: 8 -- Over: (-110) | Under: (-110)

Astros vs Angels Probable Starting Pitchers

Probable Pitchers: Spencer Arrighetti (Astros) - 7-13, 4.68 ERA vs Griffin Canning (Angels) - 6-13, 5.21 ERA

This contest's pitching matchup is set, as the Astros will send Spencer Arrighetti (7-13) to the mound, while Griffin Canning (6-13) will answer the bell for the Angels. When Arrighetti starts, his team is 11-16-0 against the spread this season. When Arrighetti starts a game and his team is the favorite on the moneyline, they have a record of 7-11. The Angels have a 15-13-0 record against the spread in Canning's starts. The Angels are 9-14 in Canning's 23 starts this season that they were the underdog on the moneyline.

Astros vs Angels Prediction & Pick

All MLB win probability predictions and picks are according to numberFire.
Prediction: Astros win (66.2%)

Astros vs Angels Moneyline

• Houston is the favorite, -275 on the moneyline, while Los Angeles is a +225 underdog on the road.

Astros vs Angels Spread

• The Astros are favored by 1.5 runs at home versus the Angels. The Astros are -128 to cover the spread, while the Angels are +106.

Astros vs Angels Over/Under

• The over/under for the Astros versus Angels game on Sept. 22 has been set at 8, with -110 odds on the over and -110 odds on the under.

Bet on Houston Astros vs. Los Angeles Angels on FanDuel today!

Astros vs Angels Betting Trends

• The Astros have won in 65, or 58%, of the 112 contests they have been named as odds-on favorites in this year.
• This year Houston has won four of five games when listed as at least -275 on the moneyline.
• Contests with the Astros have gone over the total set by sportsbooks in 63 of 155 chances this season.
• The Astros are 78-77-0 against the spread in their 155 games with a line set by sportsbooks this season.
• The Angels have won 52 of the 125 games they were the moneyline underdog this season (41.6%).
• Los Angeles has played in three games as a moneyline underdog with odds of +225 or longer without earning a win.
• The Angels have played in 153 games with an over/under set, and have combined with opponents to go over the total 71 times (71-73-9).
• The Angels have put together an 80-73-0 record against the spread this season.

Astros Player Leaders

• Yordan Alvarez leads Houston in OBP (.390) and total hits (168) this season. He's batting .305 batting average while slugging .564.
• He ranks sixth in batting average, fourth in on-base percentage, and sixth in slugging among qualifying hitters in MLB.
• Jose Altuve has hit 19 homers this season while driving in 64 runs. He's batting .296 this season and slugging .436 with an on-base percentage of .351.
• Among all qualifying hitters, he ranks 10th in batting average, 26th in on-base percentage and 58th in slugging percentage.
• Alex Bregman is batting .254 with a .438 slugging percentage and 70 RBI this year.
• Yainer Diaz has been key for Houston with 169 hits, an OBP of .325 plus a slugging percentage of .445.
• Diaz brings a three-game hitting streak into this game. During his last five outings he is batting .333 with two doubles and an RBI.

Angels Player Leaders

• Zachary Neto is hitting .245 with 32 doubles, a triple, 21 home runs and 38 walks. He's slugging .429 with an on-base percentage of .314.
• He is 89th in batting average, 90th in on-base percentage and 62nd in slugging percentage among all qualified hitters in the majors.
• Taylor Ward leads his team with 139 hits and has a club-best .437 slugging percentage. He has a batting average of .249 with an on-base percentage of .324.
• He is currently 76th in batting average, 70th in on-base percentage and 57th in slugging percentage among all qualifying hitters.
• Nolan Schanuel has a team-high .346 on-base percentage.
• Logan O'Hoppe is batting .239 with 16 doubles, a triple, 20 home runs and 30 walks.

Astros vs Angels Head to Head

• 9/21/2024: 10-4 HOU (Favorite: Astros, Spread: -1.5, Total: 7.5, Favorite Moneyline: -230, Underdog Moneyline: +190)
• 9/20/2024: 9-7 HOU (Favorite: Astros, Spread: -1.5, Total: 8, Favorite Moneyline: -255, Underdog Moneyline: +210)
• 9/19/2024: 3-1 HOU (Favorite: Astros, Spread: -1.5, Total: 8, Favorite Moneyline: -290, Underdog Moneyline: +235)
• 9/15/2024: 6-4 HOU (Favorite: Astros, Spread: -1.5, Total: 9, Favorite Moneyline: -200, Underdog Moneyline: +168)
• 9/14/2024: 5-3 HOU (Favorite: Astros, Spread: -1.5, Total: 8.5, Favorite Moneyline: -158, Underdog Moneyline: +134)
• 9/13/2024: 5-3 HOU (Favorite: Astros, Spread: -1.5, Total: 8.5, Favorite Moneyline: -215, Underdog Moneyline: +180)
• 6/9/2024: 9-7 LAA (Favorite: Astros, Spread: -1.5, Total: 8.5, Favorite Moneyline: -154, Underdog Moneyline: +130)
• 6/8/2024: 6-1 HOU (Favorite: Astros, Spread: -1.5, Total: 8.5, Favorite Moneyline: -176, Underdog Moneyline: +148)
• 6/7/2024: 7-1 HOU (Favorite: Astros, Spread: -1.5, Total: 8.5, Favorite Moneyline: -164, Underdog Moneyline: +138)
• 5/22/2024: 2-1 LAA (Favorite: Astros, Spread: -1.5, Total: 9, Favorite Moneyline: -200, Underdog Moneyline: +168)

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