Arkansas vs Missouri College Basketball Prediction, Odds, Picks, Best Bets for Feb. 21

SEC action features the No. 20 Arkansas Razorbacks (19-7, 9-4 SEC) at home against the Missouri Tigers (18-8, 8-5 SEC) on Saturday, February 21, 2026 at 4 p.m. ET.

Before you place your bet on this matchup at FanDuel Sportsbook, here are the NCAA basketball odds and spreads you need to know.

Arkansas vs. Missouri Game Info and Odds

• Game day: Saturday, February 21, 2026
• Game time: 4 p.m. ET
• TV channel: ESPN
• Location: Fayetteville, Arkansas
• Arena: Bud Walton Arena

Arkansas vs. Missouri Picks and Prediction

All college basketball win probability predictions and picks are according to numberFire.
Prediction: Arkansas win (82.7%)

Take a look at some betting trends and insights for Arkansas (-10.5) versus Missouri on Saturday. The total is set at 159.5 points for this game.

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Arkansas vs. Missouri: ATS Betting Stats and Trends

• Arkansas has covered 18 times in 26 games with a spread this season.
• Missouri is 11-15-0 ATS this season.
• Arkansas (7-3) covers a higher percentage of games when it is favored by 10.5 points or more this season (70%) than Missouri (1-1) does as a 10.5+-point underdog (50%).
• Against the spread, the Razorbacks have performed better at home, covering 10 times in 14 home games, and five times in eight road games.
• Against the spread, the Tigers have had better results away (4-4-0) than at home (7-9-0).
• Arkansas has nine wins against the spread in 13 conference games this year.
• Missouri has six wins against the spread in 13 SEC games this season.

Arkansas vs. Missouri: Moneyline Betting Stats

• Arkansas has been victorious in 15, or 93.8%, of the 16 contests it has been chosen as moneyline favorites in this season.
• The Razorbacks have been a -599 moneyline favorite on eight occasions this season and won every game.
• Missouri has won 50% of the games this season it was the moneyline underdog (5-5).
• The Tigers have a record of 1-2 in games they have played as a moneyline underdog with odds of +430 or longer (33.3%).
• The moneyline set for this matchup implies Arkansas has a 85.7% chance of walking away with the win.

Arkansas vs. Missouri Head-to-Head Comparison

• Arkansas' +305 scoring differential (outscoring opponents by 11.8 points per game) is a result of scoring 89.8 points per game (eighth in college basketball) while allowing 78.0 per contest (289th in college basketball).
• Darius Acuff Jr.'s team-leading 22.3 points per game ranks eighth in the country.
• Missouri's +144 scoring differential (outscoring opponents by 5.6 points per game) is a result of putting up 80.1 points per game (98th in college basketball) while allowing 74.5 per contest (206th in college basketball).
• Mark Mitchell paces Missouri, putting up 16.9 points per game (157th in college basketball).
• The Razorbacks record 32.4 rebounds per game (164th in college basketball) compared to the 31.7 of their opponents.
• Trevon Brazile averages 7.2 rebounds per game (ranking 129th in college basketball) to lead the Razorbacks.
• The Tigers win the rebound battle by 4.3 boards on average. They record 33.0 rebounds per game, 127th in college basketball, while their opponents grab 28.7.
• Mitchell averages 5.5 rebounds per game (407th in college basketball) to lead the Tigers.
• Arkansas' 109.1 points per 100 possessions on offense rank 12th in college basketball, and the 94.8 points it allows per 100 possessions rank 182nd in college basketball.
• The Tigers rank 74th in college basketball with 102.4 points scored per 100 possessions, and 207th defensively with 95.4 points conceded per 100 possessions.

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