Alabama vs Oklahoma Prediction, Odds, Picks, Best Bets for 2025 CFP First Round

The Oklahoma Sooners are among the college football teams playing on Friday, versus the Alabama Crimson Tide.

Get the latest NCAA football odds ahead of this game on FanDuel Sportsbook.

Oklahoma vs Alabama Odds & Spread

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• All college football odds, betting lines and prop bets are available on FanDuel Sportsbook.
• Moneyline: Oklahoma: (-112) | Alabama: (-104)
• Spread: Oklahoma: -1.5 (-106) | Alabama: +1.5 (-114)
• Total: 40.5 -- Over: (-115) | Under: (-105)

Oklahoma vs Alabama Betting Trends

• Oklahoma has seven wins in 12 games against the spread this season.
• As 1.5-point favorites or more, Oklahoma is 5-4 against the spread.
• Two of Oklahoma's 12 games have hit the over.
• Alabama's record against the spread in 2025 is 8-5-0.
• Alabama has won once ATS (1-1) as a 1.5-point underdog or more this season.
• There have been four Alabama games (out of 13) that went over the total this season.

Oklahoma vs Alabama Prediction & Pick

All college football win probability predictions and picks are according to numberFire.
Prediction: Sooners win (53.2%)

Oklahoma vs Alabama Point Spread

Alabama is the underdog by 1.5 points against Oklahoma. Alabama is -106 to cover the spread, and Oklahoma is -114.

Oklahoma vs Alabama Over/Under

An over/under of 40.5 has been set for Oklahoma-Alabama on Dec. 19, with the over being -115 and the under -105.

Oklahoma vs Alabama Moneyline

The moneyline numbers for Oklahoma vs. Alabama reveal Oklahoma as the favorite (-112) and Alabama as the underdog (-104).

Oklahoma vs. Alabama Points Insights

Oklahoma vs. Alabama Game Info

• Game day: Friday, December 19, 2025
• Game time: 8 p.m. ET
• TV channel: ABC
• Location: Norman, Oklahoma
• Stadium: Gaylord Family Oklahoma Memorial Stadium

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Check out even more in-depth Oklahoma vs. Alabama analysis on FanDuel Research.