76ers vs. Lakers Prediction, Odds, Picks, Best Bets for Dec. 7

76ers vs. Lakers Game Info

• Date: Sunday, December 7, 2025
• Time: 7:30 p.m. ET
• Venue: Xfinity Mobile Arena -- Philadelphia, Pennsylvania
• Coverage: SportsNet LA and NBCS-PH

Tyrese Maxey and the Philadelphia 76ers (13-9) are 3.5-point underdogs against Luka Doncic and the Los Angeles Lakers (16-6) Sunday, December 7, 2025 at Xfinity Mobile Arena. The matchup starts at 7:30 p.m. ET on SportsNet LA and NBCS-PH. The matchup has an over/under of 233.5.

76ers vs. Lakers Odds & Spread

All NBA betting lines, odds and prop bets are from FanDuel Sportsbook.

76ers vs. Lakers Prediction & Pick

All NBA win probability predictions and picks are according to numberFire.
Prediction: Lakers win (55%)

76ers vs. Lakers Betting Trends

• The Lakers have covered the spread in a game 14 times this season (14-8-0).
• The 76ers have 11 wins against the spread in 22 games this year.
• Lakers games have finished with a final combined score above the over/under 16 times this season.
• 76ers games this season have eclipsed the over/under 50% of the time (11 out of 22 games with a set point total).
• Los Angeles has covered the spread in a lower percentage of its home games than road games. It has covered six times in 10 games at home, and it has covered eight times in 12 games on the road.
• The Lakers have gone over the total more consistently when playing at home, hitting the over in 10 of 10 home matchups (100%). In away games, they have hit the over in six of 12 games (50%).
• Philadelphia has performed better against the spread on the road (6-3-0) than at home (5-7-1) this season.
• 76ers games have gone above the over/under 46.2% of the time at home (six of 13), and 55.6% of the time away (five of nine).

Lakers Leaders

• Doncic averages 35.3 points, 8.9 boards and 8.9 assists, shooting 47.8% from the floor and 34.1% from beyond the arc, with 3.7 made treys per game (second in NBA).
• Austin Reaves averages 29.3 points, 5.5 rebounds and 6.8 assists, shooting 52.5% from the field and 37.2% from downtown, with 2.9 made treys per game.
• Deandre Ayton's numbers on the season are 15.4 points, 8.7 boards and 0.9 assists per game, shooting 69.6% from the floor (second in NBA).
• Rui Hachimura averages 13.9 points, 3.8 rebounds and 0.8 assists, shooting 53.3% from the field and 46.5% from downtown (eighth in league), with 1.9 made 3-pointers per contest.
• Jake Laravia averages 9.1 points, 3.9 boards and 1.9 assists, shooting 46.8% from the field and 33.8% from downtown, with 1 made treys per contest.

76ers Leaders

• Maxey is averaging 31.6 points, 4.6 boards and 7.1 assists for the 76ers.
• The 76ers are getting 17 points, 3.9 rebounds and 4.4 assists per game from Quentin Grimes.
• The 76ers receive 14.3 points per game from VJ Edgecombe, plus 5.7 boards and 4.1 assists.
• Andre Drummond's numbers on the season are 7.5 points, 9.2 boards and 0.8 assists per contest. He is sinking 55.3% of his shots from the field.
• The 76ers are receiving 18.5 points, 5.4 rebounds and 3.1 assists per game from Joel Embiid.

For more NBA betting insights, check out FanDuel Research's NBA home page.

Sign up for FanDuel Sportsbook and FanDuel Daily Fantasy today!

Watch FanDuel TV's NBA show "Run It Back" with Lou Williams, Michelle Beadle, DeMarcus "Boogie" Cousins and Chandler Parsons weekdays at 10am ET on FanDuel TV, the Run It Back YouTube page, or download the podcast here: fanduel.com/research/tv-and-podcast.