Thursday Night Football Fantasy Picks: Start 'Em, Sit 'Em for Cardinals vs Seahawks

The Arizona Cardinals take on the Seattle Seahawks in a rematch of one of the best games of the 2020 season. A whopping 71 total points were scored when these two met back in Week 7, and that could lead to some monster fantasy football performances in round two.

If you need some help with your lineups, here's some start 'em, sit 'em advice for Thursday night's marquee NFC West showdown.

Who Should I Start Fantasy Football

Start Christian Kirk, WR, Arizona Cardinals: Cardinals' wideout Christian Kirk is definitely a bit of a boom-or-bust player, but he's been falling on the "boom" side of things a lot recently. He's put up at least 20.0 PPR points in three of his last four games – one of which came in Week 7 against this very secondary. Speaking of Seattle's secondary, it's absolutely horrendous. The Seahawks are on pace to allow more passing yards than any team in NFL history. In fact, they're on track to top that mark by about 900 yards. Kirk is on a roll right now and there's no reason to think he'll slow down against one of the worst pass defenses the NFL has ever seen.

Start Tyler Lockett, WR, Seattle Seahawks: Tyler Lockett looked to be in danger of missing this game, but head coach Pete Carroll confirmed he'll be out there on Thursday. The knee injury may make some fantasy managers hesitant, but you just can't leave Lockett on the bench this week. He absolutely demolished Arizona's secondary when these two met in Week 7. With DK Metcalf shut down by Patrick Peterson, Russell Wilson was forced to funnel targets Lockett's way. The Kansas State product responded with 15 catches for 200 yards and 3 touchdowns. He's a little riskier than he usually would be, but you can't ignore that upside.

Sit Kenyan Drake, RB, Arizona Cardinals: While the Seahawks have struggled to defend the pass, they've actually been pretty stout against the run. Seattle ranks No. 9 against the run in Football Outsiders' DVOA metrics, surrendering just 3.7 yards per carry (No. 4 in the NFL). That means Kenyan Drake is likely going to be in for an inefficient day on the ground. And with Seattle being 3-point favorites, Arizona might not be running the ball all that often. If Arizona is playing from behind Chase Edmonds is likely going to keep Drake off the field, as he averages 1.4 targets per outing compared to 4.2 for Edmonds. The legitimate concerns about his volume and efficiency make Drake little more than a FLEX option here.

Sit David Moore, WR, Seattle Seahawks: When it looked like Lockett was in danger of missing this game, David Moore started generating some real fantasy buzz. But Moore shouldn't be on the fantasy radar now that Lockett's back in the mix. Moore is only averaging 3.2 targets per game and has only topped 3 targets twice in nine outings. Even with this passing game being as dangerous as it is, you don't want to start any WR seeing target numbers that low.

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Max Staley is not a FanDuel employee. In addition to providing DFS gameplay advice, Max Staley also participates in DFS contests on FanDuel using his personal account, username mstaley1212. While the strategies and player selections recommended in his articles are his personal views, he may deploy different strategies and player selections when entering contests with his personal account. The views expressed in their articles are the author's alone and do not necessarily reflect the views of FanDuel.