College Football Predictions: 3 Best Bets & Props for Today's Games With Odds & Picks

College Football Betting Picks in Summary

• Washington -23.5
• Notre Dame -20.5
• Ole Miss -6.5

Three notable games round out today's college football slate, ranging from a pair of ranked teams handling in-state and rivalry business to a genuine top-25 showdown between Louisville and Ole Miss.

All college football odds come from FanDuel Sportsbook's college football betting odds and may change after this article is published.

College Football Predictions and Picks

Washington State at Washington (4:00 p.m. ET)

Washington -23.5 (-110)

Ranked No. 17 and hosting a rivalry matchup, Washington's -2800 moneyline reflects a real, well-established gap between these two programs at this point.

Wisconsin at Notre Dame (7:30 p.m. ET)

Notre Dame -20.5 (-110)

Ranked No. 4 in prime time at home, Notre Dame's -1800 moneyline is a genuine statement from the market about the gap between these two programs to open the season.

Louisville at Ole Miss (7:30 p.m. ET)

Ole Miss -6.5 (-118)

This is genuinely the most competitive game of the three — No. 24 Louisville visiting No. 9 Ole Miss, with a modest home-field number and a total near 55 pointing to a real, back-and-forth showdown between two ranked teams.