White Sox vs Twins Prediction, Odds, Moneyline, Spread & Over/Under for Sept. 5

Odds updated as of 6:13 p.m.

The Chicago White Sox versus the Minnesota Twins is on the MLB schedule for Saturday.

Before checking out the MLB betting lines on FanDuel Sportsbook, we've got you covered, in terms of the most important info about this matchup.

White Sox vs Twins Game Info

• Chicago White Sox (74-67) vs. Minnesota Twins (67-74)
• Date: Saturday, September 5, 2026
• Time: 7:10 p.m. ET
• Venue: Rate Field -- Chicago, Illinois
• Coverage: CHSN and Twins.TV

White Sox vs Twins Odds & Moneyline

• All MLB odds, betting lines and prop bets are available on FanDuel Sportsbook.
• Moneyline: CHW: (-124) | MIN: (+106)
• Spread: CHW: -1.5 (+168) | MIN: +1.5 (-205)
• Total: 8.5 -- Over: (+100) | Under: (-122)

White Sox vs Twins Probable Starting Pitchers

Probable Pitchers: Anthony Kay (White Sox) - 9-7, 4.35 ERA vs Taj Bradley (Twins) - 10-6, 3.85 ERA

The probable starters are Anthony Kay (9-7) for the White Sox and Taj Bradley (10-6) for the Twins. Kay's team is 18-7-0 against the spread this season in his starts. Kay's team has won 33.3% of his starts when they are favored on the moneyline (1-2). The Twins are 17-9-0 ATS in Bradley's 26 starts with a set spread. The Twins are 9-6 in Bradley's 15 starts this season that they were the moneyline underdog.

White Sox vs Twins Prediction & Pick

All MLB win probability predictions and picks are according to numberFire.
Prediction: Twins win (54.4%)

White Sox vs Twins Moneyline

• Chicago is the favorite, -124 on the moneyline, while Minnesota is a +106 underdog on the road.

White Sox vs Twins Spread

• The White Sox are hosting the Twins and are favored by 1.5 runs on the spread. The White Sox are +168 to cover the runline, with the Twins being -205.

White Sox vs Twins Over/Under

• White Sox versus Twins on Sept. 5 has an over/under of 8.5 runs, with the odds on the over +100 and the under set at -122.

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White Sox vs Twins Betting Trends

• The White Sox have won in 18, or 60%, of the 30 contests they have been named as odds-on favorites in this year.
• This season Chicago has come away with a win 10 times in 16 chances when named as a favorite of at least -124 on the moneyline.
• The White Sox and their opponents have hit the over in 75 of their 138 games with a total set by oddsmakers this season.
• The White Sox have posted a record of 80-58-0 against the spread this season.
• The Twins have put together a 36-46 record in games they were the underdog on the moneyline (winning 43.9% of those games).
• When it has played as a moneyline underdog with odds of +106 or longer, Minnesota has gone 30-35 (46.2%).
• The Twins have played in 138 games with an over/under set, and have combined with their opponents to go over the total 77 times (77-58-3).
• The Twins have covered 53.6% of their games this season, going 74-64-0 against the spread.

White Sox Player Leaders

• Miguel Vargas leads Chicago with 129 hits and an OBP of .363 this season. He has a .251 batting average and a slugging percentage of .488.
• Among qualified hitters in the majors, he is 77th in batting average, 23rd in on-base percentage, and 19th in slugging.
• Vargas has recorded at least one hit in two straight games. During his last five outings he is hitting .300 with a home run, two walks and an RBI.
• Chase Meidroth leads Chicago in slugging percentage (.397) thanks to 39 extra-base hits. He's batting .271 with an on-base percentage of .344.
• Among qualifying hitters, his batting average places him 41st, his on-base percentage 48th, and his slugging percentage 94th.
• Sam Antonacci leads Chicago with an OBP of .363 this season while batting .264 with 40 walks and 70 runs scored.
• Antonacci brings a two-game hitting streak into this game. In his last five games he is batting .167 with three walks and an RBI.
• Tristan Peters has been key for Chicago with 107 hits, an OBP of .346 plus a slugging percentage of .467.

Twins Player Leaders

• Brooks Lee is hitting .248 with 21 doubles, three triples, 22 home runs and 33 walks. He's slugging .432 with an on-base percentage of .297.
• He is 83rd in batting average, 122nd in on-base percentage and 58th in slugging percentage among all qualifying hitters in MLB.
• Josh Bell's .425 slugging percentage paces his team. He has a batting average of .258 with an on-base percentage of .322.
• He is currently 64th in batting average, 86th in on-base percentage and 61st in slugging percentage among all qualifying hitters.
• Kody Clemens paces the Twins with 110 hits.
• Luke Keaschall has a .365 on-base percentage to lead his team.

White Sox vs Twins Head to Head

• 9/4/2026: 4-1 CHW (Favorite: White Sox, Spread: -1.5, Total: 9, Favorite Moneyline: -120, Underdog Moneyline: +102)
• 8/30/2026: 5-1 MIN (Favorite: Twins, Spread: -1.5, Total: 9, Favorite Moneyline: -114, Underdog Moneyline: +104)
• 8/29/2026: 3-2 CHW (Favorite: Twins, Spread: -1.5, Total: 9, Favorite Moneyline: -110, Underdog Moneyline: +100)
• 8/28/2026: 7-4 CHW (Favorite: Twins, Spread: -1.5, Total: 8.5, Favorite Moneyline: -126, Underdog Moneyline: +116)
• 6/3/2026: 8-0 CHW (Favorite: Twins, Spread: -1.5, Total: 9, Favorite Moneyline: -154, Underdog Moneyline: +130)
• 6/2/2026: 6-4 MIN (Favorite: White Sox, Spread: -1.5, Total: 7.5, Favorite Moneyline: -120, Underdog Moneyline: +102)
• 6/1/2026: 9-6 MIN (Favorite: Twins, Spread: -1.5, Total: 7.5, Favorite Moneyline: -144, Underdog Moneyline: +122)
• 5/28/2026: 6-2 CHW (Favorite: White Sox, Spread: -1.5, Total: 8, Favorite Moneyline: -178, Underdog Moneyline: +150)
• 5/27/2026: 15-2 CHW (Favorite: White Sox, Spread: -1.5, Total: 7.5, Favorite Moneyline: -108, Underdog Moneyline: -108)
• 5/26/2026: 5-3 MIN (Favorite: Twins, Spread: -1.5, Total: 7.5, Favorite Moneyline: -116, Underdog Moneyline: -102)

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