Virginia vs Duke Prediction, Odds, Picks, Best Bets for Week 8 2026

College football's Friday schedule includes the Virginia Cavaliers taking on the Duke Blue Devils.

Get the latest NCAA football odds ahead of this game on FanDuel Sportsbook.

Virginia vs Duke Odds & Spread

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• All college football odds, betting lines and prop bets are available on FanDuel Sportsbook.
• Moneyline: Virginia: (-122) | Duke: (+102)
• Spread: Virginia: -1.5 (-112) | Duke: +1.5 (-108)
• Total: 47.5 -- Over: (-110) | Under: (-110)

Virginia vs Duke Betting Trends

• Virginia has beaten the spread three times in seven games.
• As 1.5-point favorites or more, Virginia is 3-3 against the spread.
• This season, three of Virginia's seven games have hit the over.
• Duke's record against the spread in 2026 is 4-2-0.
• Duke has covered every time (1-0) as a 1.5-point or greater underdog this season.
• Duke has played six games this year, and three of them have hit the over.

Virginia vs Duke Prediction & Pick

All college football win probability predictions and picks are according to numberFire.
Prediction: Cavaliers win (59.3%)

Virginia vs Duke Point Spread

Virginia is a 1.5-point favorite against Duke. Virginia is -112 to cover the spread, and Duke is -108.

Virginia vs Duke Over/Under

Virginia versus Duke on Oct. 23 has an over/under of 47.5 points, with the over -110 and the under -110.

Virginia vs Duke Moneyline

Looking at the moneyline for Duke-Virginia, Duke is the underdog at +102, and Virginia is -122.

Virginia vs. Duke Points Insights

Virginia vs. Duke Game Info

• Game day: Friday, October 23, 2026
• Game time: 7 p.m. ET
• TV channel: ESPN
• Location: Charlottesville, Virginia
• Stadium: Scott Stadium

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Check out even more in-depth Virginia vs. Duke analysis on FanDuel Research.