Vanderbilt vs Western Kentucky College Basketball Prediction, Odds, Picks, Best Bets for Nov. 26

The Vanderbilt Commodores (5-0) will try to continue a five-game winning streak when they host the Western Kentucky Hilltoppers (4-0) on November 26, 2025. The Hilltoppers have won four games in a row.

Before you place your bet on this matchup at FanDuel Sportsbook, here are the NCAA basketball odds and spreads you need to know.

Vanderbilt vs. Western Kentucky Game Info and Odds

• Game day: Wednesday, November 26, 2025
• Game time: 12 p.m. ET
• TV channel: ESPN
• Location: Nassau, Bahamas
• Arena: Imperial Arena

Vanderbilt vs. Western Kentucky Picks and Prediction

All college basketball win probability predictions and picks are according to numberFire.
Prediction: Vanderbilt win (84.2%)

Vanderbilt is a 17.5-point favorite over Western Kentucky on Wednesday and the total is set at 168.5 points. Here are a few betting insights and trends to help you make an informed wager on the contest.

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Vanderbilt vs. Western Kentucky: ATS Betting Stats and Trends

• Vanderbilt compiled a 20-13-0 ATS record last year.
• Western Kentucky won 15 games against the spread last year, while failing to cover 15 times.
• When the spread was set as 17.5 or more last season, Vanderbilt (5-2) covered a higher percentage of those games when it was the favorite (71.4%) than Western Kentucky (1-1) did as the underdog (50%).
• Against the spread last season, the Commodores performed better at home, covering 11 times in 17 home games, and five times in 10 road games.
• In 2024-25 against the spread, the Hilltoppers had a lower winning percentage at home (.500, 8-8-0 record) than away (.538, 7-6-0).

Vanderbilt vs. Western Kentucky: Moneyline Betting Stats

• Vanderbilt won 14 of the 17 games it was the moneyline favorite last season (82.4%).
• The Commodores won all six games they played as a moneyline favorite with odds of -3448 or shorter.
• Western Kentucky was underdogs in 12 games last season and won three (25%) of those contests.
• The Hilltoppers played as an underdog of +1280 or more twice last season and lost both games.
• Vanderbilt has an implied moneyline win probability of 97.2% in this game.

Vanderbilt vs. Western Kentucky Head-to-Head Comparison

• At 78.9 points scored per game and 74.3 points conceded last year, Vanderbilt was 55th in the nation offensively and 249th defensively.
• On the glass, Vanderbilt was 221st in the country in rebounds (31.2 per game) last year. It was 226th in rebounds conceded (31.9 per game).
• At 13.8 assists per game last season, Vanderbilt was 158th in the nation.
• Vanderbilt was 40th in the country in turnovers per game (9.6) and 40th in turnovers forced (13.4) last year.
• Western Kentucky put up 74.8 points per game (143rd-ranked in college basketball) last season, while ceding 74.8 points per contest (263rd-ranked).
• Western Kentucky, who ranked 96th in college basketball with 33.3 boards per game, allowed 37.5 rebounds per contest, which was -4-worst in college basketball.
• Western Kentucky ranked 295th in the nation with 11.9 dimes per game.
• Western Kentucky ranked 120th in college basketball with 10.5 turnovers per game last year. Meanwhile, it ranked 121st with 11.9 forced turnovers per game.

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