Vanderbilt vs SMU College Basketball Prediction, Odds, Picks, Best Bets for Dec. 3

A pair of streaking teams meet when the Vanderbilt Commodores (8-0) host the SMU Mustangs (8-0) on December 3, 2025. The Commodores will put their eight-game win streak on the line against the Mustangs, winners of eight straight.

Before you place your bet on this game at FanDuel Sportsbook, here are the NCAA basketball odds and spreads you need to know.

Vanderbilt vs. SMU Game Info and Odds

• Game day: Wednesday, December 3, 2025
• Game time: 9:15 p.m. ET
• TV channel: SEC Network
• Location: Nashville, Tennessee
• Arena: Memorial Gymnasium

Before you bet on Wednesday's Vanderbilt-SMU spread (Vanderbilt -11.5) or over/under (166.5 points), read the betting trends and insights below.

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Vanderbilt vs. SMU: ATS Betting Stats and Trends

• Vanderbilt has compiled a 5-3-0 ATS record so far this year.
• SMU is 4-4-0 ATS this season.
• The Commodores owned a better record against the spread at home (11-6-0) than they did in road games (5-5-0) last season.
• In 2024-25 against the spread, the Mustangs had a lower winning percentage at home (.412, 7-10-0 record) than on the road (.455, 5-6-0).

Vanderbilt vs. SMU: Moneyline Betting Stats

• Vanderbilt has yet to lose any of the six games it has been chosen as the moneyline favorite in this season.
• The Commodores have yet to lose in four games when named as moneyline favorite of -649 or better.
• SMU has been listed as the moneyline underdog only one other time so far this season, a game it won.
• The Mustangs have not yet played as a moneyline underdog of +460 or longer.
• Sportsbooks have implied with the moneyline set for this matchup that Vanderbilt has a 86.6% chance of pulling out a win.

Vanderbilt vs. SMU Head-to-Head Comparison

• Offensively, Vanderbilt was the 55th-ranked squad in the country (78.9 points per game) last year. On defense, it was 249th (74.3 points conceded per game).
• Vanderbilt was 221st in college basketball in rebounds per game (31.2) and 226th in rebounds allowed (31.9) last season.
• Last season Vanderbilt was ranked 158th in the nation in assists with 13.8 per game.
• Last year, Vanderbilt was 40th in the country in turnovers committed (9.6 per game) and 40th in turnovers forced (13.4).
• SMU was 40th in the country last year with 79.9 points per game. At the other end of the court, it ranked 152nd with 71.3 points allowed per game.
• SMU grabbed 34.7 rebounds per game (43rd-ranked in college basketball) last year, while allowing 29 rebounds per contest (53rd-ranked).
• SMU averaged 15.9 dimes per game, which ranked them 42nd in the country.
• Last year SMU averaged 11.5 turnovers per game (221st-ranked in college basketball) and forced 12 turnovers per contest (112th-ranked).

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