UConn vs DePaul College Basketball Prediction, Odds, Picks, Best Bets for Jan. 10

The UConn Huskies (15-1, 5-0 Big East) will attempt to continue a seven-game home win streak when they square off against the DePaul Blue Demons (10-6, 2-3 Big East) on January 10, 2026 at PeoplesBank Arena.

Before you place your bet on this matchup at FanDuel Sportsbook, here are the NCAA basketball odds and spreads you need to know.

UConn vs. DePaul Game Info and Odds

• Game day: Saturday, January 10, 2026
• Game time: 12:30 p.m. ET
• TV channel: TNT
• Location: Hartford, Connecticut
• Arena: PeoplesBank Arena

UConn vs. DePaul Picks and Prediction

All college basketball win probability predictions and picks are according to numberFire.
Prediction: UConn win (92.9%)

Before making a wager on Saturday's UConn-DePaul spread (UConn -19.5) or total (136.5 points), read the betting trends and insights below.

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UConn vs. DePaul: ATS Betting Stats and Trends

• UConn has covered six times in 16 chances against the spread this season.
• DePaul has put together a 10-6-0 record against the spread this season.
• UConn covers the spread when it is a 19.5-point favorite or more 20% of the time. That's less often than DePaul covers as an underdog of 19.5 or more (100%).
• At home, the Huskies own a worse record against the spread (2-7-0) compared to their ATS record in away games (3-1-0).
• The Blue Demons were better against the spread at home (9-10-0) than away (5-7-0) last season.
• UConn is 3-2-0 against the spread in conference action this year.
• DePaul is 4-1-0 against the spread in Big East games this season.

UConn vs. DePaul: Moneyline Betting Stats

• UConn has been the moneyline favorite in 11 games this season and has come away with the win 10 times (90.9%) in those contests.
• This is the best odds of a victory sportsbooks have given the Huskies this season with a -4545 moneyline set for this game.
• DePaul has won one of the six games it was listed as the moneyline underdog this season (16.7%).
• The Blue Demons have not yet played as a moneyline underdog of +1600 or longer.
• UConn has an implied victory probability of 97.8% according to the moneyline set for this matchup.

UConn vs. DePaul Head-to-Head Comparison

• UConn averages 80.4 points per game (117th in college basketball) while allowing 63.5 per contest (11th in college basketball). It has a +270 scoring differential overall and outscores opponents by 16.9 points per game.
• UConn's leading scorer, Solomon Ball, is 255th in college basketball averaging 15.3 points per game.
• DePaul is outscoring opponents by 5.3 points per game, with a +84 scoring differential overall. It puts up 73.7 points per game (260th in college basketball) and allows 68.4 per outing (69th in college basketball).
• DePaul's leading scorer, CJ Gunn, is 434th in the country, putting up 13.7 points per game.
• The Huskies average 34.4 rebounds per game (116th in college basketball) while allowing 27.8 per contest to their opponents. They outrebound opponents by 6.6 boards per game.
• Alex Karaban tops the team with 5.3 rebounds per game (475th in college basketball play).
• The Blue Demons rank 241st in the country at 31.8 rebounds per game. That's similar to the 31.8 their opponents average.
• N.J. Benson averages 7.1 rebounds per game (149th in college basketball) to lead the Blue Demons.
• UConn's 104.4 points per 100 possessions on offense rank 63rd in college basketball, and the 82.5 points it allows per 100 possessions rank 17th in college basketball.
• The Blue Demons' 94.4 points per 100 possessions on offense rank 241st in college basketball, and the 87.7 points they concede per 100 possessions rank 69th in college basketball.

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