Twins vs Guardians Prediction, Odds, Moneyline, Spread & Over/Under for May 19

Odds updated as of 7:11 a.m.

In MLB action on Monday, the Minnesota Twins face the Cleveland Guardians.

Here's everything you need to know before checking out today's MLB odds and spreads on FanDuel Sportsbook.

Twins vs Guardians Game Info

• Minnesota Twins (26-21) vs. Cleveland Guardians (25-21)
• Date: Monday, May 19, 2025
• Time: 7:40 p.m. ET
• Venue: Target Field -- Minneapolis, Minnesota
• Coverage: MNNT and CLEG

Twins vs Guardians Odds & Moneyline

• All MLB odds, betting lines and prop bets are available on FanDuel Sportsbook.
• Moneyline: MIN: (-142) | CLE: (+120)
• Spread: MIN: -1.5 (+155) | CLE: +1.5 (-188)
• Total: 7.5 -- Over: (-110) | Under: (-110)

Twins vs Guardians Probable Starting Pitchers

Probable Pitchers: Bailey Ober (Twins) - 4-1, 3.72 ERA vs Logan Allen (Guardians) - 2-2, 3.70 ERA

The probable pitchers are Bailey Ober (4-1) for the Twins and Logan Allen (2-2) for the Guardians. Ober's team is 6-3-0 against the spread this season in his starts. Ober's team is 3-1 this season when he starts and they are the moneyline favorite. The Guardians are 3-5-0 against the spread when Allen starts. The Guardians have a 2-3 record in Allen's five starts this season when they were the moneyline underdog.

Twins vs Guardians Prediction & Pick

All MLB win probability predictions and picks are according to numberFire.
Prediction: Twins win (62.8%)

Twins vs Guardians Moneyline

• Cleveland is the underdog, +120 on the moneyline, while Minnesota is a -142 favorite at home.

Twins vs Guardians Spread

• The Twins are hosting the Guardians and are favored by 1.5 runs on the spread. The Twins are +155 to cover the runline, with the Guardians being -188.

Twins vs Guardians Over/Under

• The over/under for Twins-Guardians on May 19 is 7.5. The over is -110, and the under is -110.

Bet on Minnesota Twins vs. Cleveland Guardians on FanDuel today!

Twins vs Guardians Betting Trends

• The Twins have come away with 17 wins in the 29 contests they have been listed as the favorites in this season.
• This season Minnesota has come away with a win nine times in 12 chances when named as a favorite of at least -142 on the moneyline.
• The Twins and their opponents have hit the over in 16 of their 46 games with a total set by oddsmakers this season.
• In 46 games with a line this season, the Twins have a mark of 26-20-0 against the spread.
• The Guardians have won 12 of the 26 games they were the underdog on the moneyline this season (46.2%).
• Cleveland has a 4-5 record (winning 44.4% of its games) when playing as a moneyline underdog of +120 or longer.
• In the 45 games oddsmakers have set an over/under for the Guardians, they have combined with opponents to go over the total 22 times (22-21-2).
• The Guardians have covered 44.4% of their games this season, going 20-25-0 ATS.

Twins Player Leaders

• Trevor Larnach leads Minnesota OPS (.749) this season. He has a .250 batting average, an on-base percentage of .330, and a slugging percentage of .419.
• Among all qualifying hitters in baseball, he is 88th in batting average, 81st in on-base percentage, and 82nd in slugging.
• Larnach will look for his fourth straight game with a hit in this matchup. During his last five outings he is hitting .238 with a double, a triple, a home run, two walks and two RBIs.
• Ty France is batting .253 with eight doubles, three home runs and 10 walks. He's slugging .355 with an on-base percentage of .317.
• He is 83rd in batting average, 101st in on-base percentage and 133rd in slugging in the major leagues.
• Harrison Bader is batting .280 with a .432 slugging percentage and 18 RBI this year.
• Ryan Jeffers is batting .268 with a .345 OBP and 17 RBI for Minnesota this season.
• Jeffers takes a three-game hitting streak into this game. In his last five games he is hitting .364 with a double, a home run, a walk and an RBI.

Guardians Player Leaders

• Jose Ramirez leads the Guardians with 48 hits. He's batting .296 and slugging .519 with an on-base percentage of .359.
• Including all qualifying players in the big leagues, he ranks 25th in batting average, 45th in on-base percentage and 19th in slugging percentage.
• Ramirez hopes to build on a 12-game hitting streak in this matchup. In his last 10 outings he is batting .378 with two doubles, four home runs, four walks and seven RBIs.
• Steven Kwan's .374 on-base percentage and .428 slugging percentage are both team-highs. He has a batting average of .311.
• Including all qualifying hitters, his batting average places him 11th, his on-base percentage is 28th, and he is 74th in slugging.
• Kyle Manzardo has four doubles, two triples, 10 home runs and 18 walks while batting .221.
• Carlos Santana has three doubles, four home runs and 23 walks while batting .222.

Twins vs Guardians Head to Head

• 5/1/2025: 4-3 CLE (Favorite: Twins, Spread: -1.5, Total: 9, Favorite Moneyline: -124, Underdog Moneyline: +106)
• 4/30/2025: 4-2 CLE (Favorite: Twins, Spread: -1.5, Total: 7, Favorite Moneyline: -112, Underdog Moneyline: -104)
• 4/28/2025: 11-1 MIN (Favorite: Guardians, Spread: -1.5, Total: 8, Favorite Moneyline: -124, Underdog Moneyline: +106)
• 9/19/2024: 3-2 CLE (Favorite: Guardians, Spread: -1.5, Total: 8, Favorite Moneyline: -110, Underdog Moneyline: -106)
• 9/18/2024: 5-4 CLE (Favorite: Guardians, Spread: -1.5, Total: 7.5, Favorite Moneyline: -126, Underdog Moneyline: +108)
• 9/17/2024: 4-1 MIN (Favorite: Guardians, Spread: -1.5, Total: 8, Favorite Moneyline: -136, Underdog Moneyline: +116)
• 9/16/2024: 4-3 CLE (Favorite: Twins, Spread: -1.5, Total: 7.5, Favorite Moneyline: -118, Underdog Moneyline: -100)
• 8/11/2024: 5-3 CLE (Favorite: Twins, Spread: -1.5, Total: 8, Favorite Moneyline: -116, Underdog Moneyline: -102)
• 8/9/2024: 6-3 MIN (Favorite: Guardians, Spread: -1.5, Total: 8, Favorite Moneyline: -112, Underdog Moneyline: -104)
• 8/9/2024: 4-2 MIN (Favorite: Twins, Spread: -1.5, Total: 8.5, Favorite Moneyline: -162, Underdog Moneyline: +136)

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