Trail Blazers vs. Spurs Prediction, Odds, Picks, Best Bets for Nov. 26

Trail Blazers vs. Spurs Game Info

• Date: Wednesday, November 26, 2025
• Time: 10 p.m. ET
• Venue: Moda Center -- Portland, Oregon
• Coverage: KUNP and FDSSW

The Portland Trail Blazers (8-10) take the court against the San Antonio Spurs (11-5) as only 1-point favorites on Wednesday, November 26, 2025 at 10 p.m. ET on KUNP and FDSSW. The matchup has an over/under set at 240.5 points.

Trail Blazers vs. Spurs Odds & Spread

All NBA betting lines, odds and prop bets are from FanDuel Sportsbook.

Trail Blazers vs. Spurs Prediction & Pick

All NBA win probability predictions and picks are according to numberFire.
Prediction:

Trail Blazers vs. Spurs Betting Trends

• The Trail Blazers have put together a 9-9-0 record against the spread this season.
• The Spurs have six wins against the spread in 16 games this year.
• This season, Trail Blazers games have hit the over 12 times out of 16 chances.
• The Spurs have gone over the point total 50% of the time this season (eight of 16 games with a set point total).
• Portland has done a better job covering the spread at home (5-2-0) than it has in road tilts (4-7-0).
• When it comes to over/unders, the Trail Blazers hit the over more often when playing at home, as they've eclipsed the total five times in seven opportunities this season (71.4%). On the road, they have hit the over seven times in 11 opportunities (63.6%).
• Against the spread, San Antonio has performed better at home (5-3-2) than away (1-4-1).
• In terms of the over/under, Spurs games have gone over less frequently at home (four of 10, 40%) than away (four of six, 66.7%).

Trail Blazers Leaders

• Deni Avdija averages 24.9 points, 6.4 boards and 5.4 assists, shooting 46.9% from the floor and 37.4% from beyond the arc, with 2.6 made treys per game.
• Donovan Clingan averages 10.3 points, 9.9 boards and 1.7 assists, shooting 50% from the field.
• Jerami Grant averages 19.5 points, 3.5 rebounds and 2.5 assists.
• Shaedon Sharpe is averaging 22.6 points, 5 boards and 2.1 assists.
• Toumani Camara is averaging 12.1 points, 2.8 assists and 5.3 boards.

Spurs Leaders

• Devin Vassell averages 13.9 points, 3.6 rebounds and 2.6 assists. He is also sinking 40.5% of his shots from the field and 36.4% from 3-point range, with 2.5 triples per game.
• The Spurs receive 12.6 points per game from Keldon Johnson, plus 6.3 rebounds and 1.8 assists.
• The Spurs receive 12.9 points per game from Harrison Barnes, plus 3.1 boards and 2.2 assists.
• Julian Champagnie's numbers on the season are 10.4 points, 4.8 rebounds and 1.4 assists per game. He is sinking 40.9% of his shots from the field and 37.5% from 3-point range, with an average of 2.3 triples.
• De'Aaron Fox's numbers on the season are 23.5 points, 3.6 rebounds and 6.1 assists per contest. He is sinking 51.1% of his shots from the field and 38% from 3-point range, with an average of 2.4 treys.

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