St. John's vs Seton Hall College Basketball Prediction, Odds, Picks, Best Bets for March 6

Big East play on Friday will see the the No. 18 St. John's Red Storm (24-6, 17-2 Big East) visit the Seton Hall Pirates (20-10, 10-9 Big East) at Prudential Center, tipping off at 9 p.m. ET.

Before you place your bet on this game at FanDuel Sportsbook, here are the NCAA basketball odds and spreads you need to know.

St. John's vs. Seton Hall Game Info and Odds

• Game day: Friday, March 6, 2026
• Game time: 9 p.m. ET
• TV channel: Fox Sports 1
• Location: Newark, New Jersey
• Arena: Prudential Center

St. John's vs. Seton Hall Picks and Prediction

All college basketball win probability predictions and picks are according to numberFire.
Prediction: St. John's win (54.2%)

Before you bet on Friday's St. John's-Seton Hall spread (St. John's -4.5) or total (136.5 points), check out the betting insights and trends below.

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St. John's vs. Seton Hall: ATS Betting Stats and Trends

• St. John's has put together a 16-14-0 record against the spread this season.
• Seton Hall has put together an 18-12-0 ATS record so far this year.
• St. John's (12-12) covers a lower percentage of games when it is favored by 4.5 points or more this season (50%) than Seton Hall (5-1) does as a 4.5+-point underdog (83.3%).
• Against the spread, the Red Storm have performed worse when playing at home, covering eight times in 17 home games, and six times in nine road games.
• The Pirates have been better against the spread away (9-2-0) than at home (6-10-0) this year.
• St. John's record against the spread in conference games is 11-8-0.
• Against the spread in Big East play, Seton Hall is 11-8-0 this season.

St. John's vs. Seton Hall: Moneyline Betting Stats

• St. John's has been chosen as the moneyline favorite in 25 games this year and has walked away with the win 22 times (88%) in those games.
• This season, the Red Storm have come away with a win 20 times in 23 chances when named as a favorite of at least -178 or shorter on the moneyline.
• Seton Hall has compiled a 3-6 record in games it was listed as the moneyline underdog (winning 33.3% of those games).
• The Pirates have a record of 1-5 in games they have played as a moneyline underdog with odds of +146 or longer (16.7%).
• The moneyline set for this matchup implies St. John's has a 64% chance of coming away with a victory in the contest.

St. John's vs. Seton Hall Head-to-Head Comparison

• St. John's +344 scoring differential (outscoring opponents by 11.5 points per game) is a result of scoring 82.2 points per game (53rd in college basketball) while allowing 70.7 per contest (94th in college basketball).
• Zuby Ejiofor ranks 229th in college basketball with a team-high 15.8 points per game.
• Seton Hall outscores opponents by 5.7 points per game (posting 70.5 points per game, 297th in college basketball, and giving up 64.8 per contest, 10th in college basketball) and has a +171 scoring differential.
• Seton Hall's leading scorer, Adam Clark, is 652nd in college basketball, putting up 12.3 points per game.
• The Red Storm come out on top in the rebound battle by an average of 4.5 boards. They are recording 35 rebounds per game (45th in college basketball) compared to their opponents' 30.5 per contest.
• Ejiofor is 131st in college basketball play with 7.2 rebounds per game to lead the Red Storm.
• The Pirates win the rebound battle by 2.6 boards on average. They record 32.7 rebounds per game, 132nd in college basketball, while their opponents pull down 30.1.
• Stephon Payne III tops the Pirates with 6.7 rebounds per game (194th in college basketball).
• St. John's averages 100.9 points per 100 possessions on offense (104th in college basketball), and gives up 86.8 points per 100 possessions (27th in college basketball).
• The Pirates put up 93.3 points per 100 possessions (285th in college basketball), while conceding 85.7 points per 100 possessions (14th in college basketball).

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