San Diego State vs Toledo Prediction, College Football Picks, Odds & Best Bets Today

College Football Betting Picks in Summary

• Toledo -2.5
• Over 51.5
• Toledo Over 393.5 Total Yards

San Diego State travels to Toledo Saturday afternoon in a genuinely competitive matchup — a modest 2.5-point spread with real, comparable yardage projections on both sides.

All college football odds come from FanDuel Sportsbook's college football betting odds and may change after this article is published.

College Football Predictions and Picks

San Diego State at Toledo (Sat, 12:00 p.m. ET)

Toledo -2.5 (-122)

A modest home favorite in a genuinely close matchup — Toledo's own yardage total (393.5) sits just 23 yards ahead of San Diego State's (370.5), a fair reflection of the number without needing a blowout to justify it.

Over 51.5 (-105)

Both offenses carry real, sizable yardage projections — a combined 764 yards between the two team totals — pointing toward a genuine back-and-forth scoring game rather than a defensive grind.

Toledo Over 393.5 Total Yards (-114)

Toledo's rushing attack alone is projected for 221.5 yards, meaning the passing game only needs to contribute another 172 or so to clear this number — a reasonable ask for the modest home favorite.