Rockets vs. Nuggets Prediction, Odds, Picks, Best Bets for Nov. 21

Rockets vs. Nuggets Game Info

• Date: Friday, November 21, 2025
• Time: 9:30 p.m. ET
• Venue: Toyota Center -- Houston, Texas
• Coverage: Amazon Prime Video

The Houston Rockets (10-3) are 2.5-point favorites as they look to continue a five-game win streak when they host the Denver Nuggets (11-3) on Friday, November 21, 2025 at Toyota Center. The contest airs at 9:30 p.m. ET on Amazon Prime Video. The point total is 236 in the matchup.

Rockets vs. Nuggets Odds & Spread

All NBA betting lines, odds and prop bets are from FanDuel Sportsbook.

Rockets vs. Nuggets Prediction & Pick

All NBA win probability predictions and picks are according to numberFire.
Prediction: Rockets win (63%)

Rockets vs. Nuggets Betting Trends

• The Rockets are 9-4-0 against the spread this season.
• The Nuggets have nine wins against the spread in 14 games this year.
• Rockets games have gone over the total 10 times out of 14 chances this season.
• Nuggets games this season have gone over the total in eight of 14 opportunities (57.1%).
• Against the spread, Houston has performed worse when playing at home, covering three times in six home games, and six times in seven road games.
• The Rockets have exceeded the over/under in a lower percentage of games at home (66.7%) than road tilts (85.7%).
• Against the spread, Denver has performed better at home (5-2-0) than away (4-3-0).
• In terms of the over/under, Nuggets games have gone over 57.1% of the time this year, both at home (four of seven) and on the road (four of seven).

Rockets Leaders

• Alperen Sengun averages 23.4 points, 10.4 rebounds and 7.4 assists, shooting 48.9% from the floor and 44.7% from downtown, with 1.3 made 3-pointers per contest.
• Kevin Durant averages 25.5 points, 4.5 boards and 3.4 assists, shooting 49.6% from the field and 37.7% from beyond the arc, with 1.8 made 3-pointers per contest.
• Amen Thompson averages 16.8 points, 6.3 boards and 5.2 assists, shooting 46.7% from the floor.
• Jabari Smith Jr. is averaging 14.4 points, 6.6 boards and 1.7 assists.
• Reed Sheppard is averaging 12.5 points, 3.0 assists and 2.6 rebounds.

Nuggets Leaders

• Nikola Jokic averages 29.1 points for the Nuggets, plus 13.2 boards and 11.1 assists.
• Jamal Murray averages 22.5 points, 5.2 boards and 6.2 assists. He is also sinking 46.1% of his shots from the field and 35.2% from 3-point range, with 2.5 triples per contest.
• The Nuggets are getting 20.3 points, 6.3 boards and 1.4 assists per game from Aaron Gordon.
• Per game, Peyton Watson gives the Nuggets 8.2 points, 4.2 boards and 1.4 assists, plus 1.1 steals and 1.1 blocks.
• Per game, Tim Hardaway Jr. gets the Nuggets 11.1 points, 1.9 rebounds and 1.4 assists, plus 0.6 steals and 0.1 blocks.

For more NBA betting insights, check out FanDuel Research's NBA home page.

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