Pirates vs Cardinals Prediction, Odds, Moneyline, Spread & Over/Under for Aug. 29

Odds updated as of 10:12 p.m.

The Pittsburgh Pirates will take on the St. Louis Cardinals in MLB action on Saturday.

Before checking out the MLB betting lines on FanDuel Sportsbook, we've got you covered, in terms of the most important info about this game.

Pirates vs Cardinals Game Info

• Pittsburgh Pirates (65-70) vs. St. Louis Cardinals (67-68)
• Date: Saturday, August 29, 2026
• Time: 2:15 p.m. ET
• Venue: Busch Stadium -- St. Louis, Missouri
• Coverage: Cardinals.TV and SportsNet PT

Pirates vs Cardinals Odds & Moneyline

• All MLB odds, betting lines and prop bets are available on FanDuel Sportsbook.
• Moneyline: PIT: (-112) | STL: (+104)
• Spread: PIT: -1.5 (+146) | STL: +1.5 (-178)
• Total: 7.5 -- Over: (-102) | Under: (-120)

Pirates vs Cardinals Probable Starting Pitchers

Probable Pitchers: TBA (Pirates) vs Kyle Leahy (Cardinals) - 10-4, 0.00 ERA

The Cardinals will give the nod to Leahy (10-4, 3.07), while the Pirates' starting pitcher for this game has not been determined. The Cardinals are 11-12-0 against the spread when Leahy starts. The Cardinals are 6-9 in Leahy's 15 starts this season that they were the moneyline underdog.

Pirates vs Cardinals Prediction & Pick

All MLB win probability predictions and picks are according to numberFire.
Prediction: Cardinals win (55.9%)

Pirates vs Cardinals Moneyline

• Pittsburgh is a -112 favorite on the moneyline, while St. Louis is a +104 underdog at home.

Pirates vs Cardinals Spread

• The Pirates are at the Cardinals and are favored by 1.5 runs (+146 to cover) on the runline. St. Louis is -178 to cover.

Pirates vs Cardinals Over/Under

• The Pirates-Cardinals contest on Aug. 29 has been given an over/under of 7.5 runs. The over is set at -102 and the under at -120.

Bet on Pittsburgh Pirates vs. St. Louis Cardinals on FanDuel today!

Pirates vs Cardinals Betting Trends

• The Pirates have come away with 38 wins in the 68 contests they have been listed as the favorites in this season.
• This year Pittsburgh has won 36 of 65 games when listed as at least -112 on the moneyline.
• The Pirates and their opponents have hit the over in 72 of their 133 games with a total set by oddsmakers this season.
• In 133 games with a line this season, the Pirates have a mark of 65-68-0 against the spread.
• The Cardinals have been the underdog on the moneyline 89 total times this season. They've gone 41-48 in those games.
• St. Louis is 33-34 (winning 49.3% of its games) when playing as a moneyline underdog of +104 or longer.
• In the 131 games oddsmakers have set an over/under for the Cardinals, they have combined with opponents to go over the total 57 times (57-67-7).
• The Cardinals have collected a 70-61-0 record against the spread this season (covering 53.4% of the time).

Pirates Player Leaders

• Bryan Reynolds has 131 hits this season and a team-best OBP of .370. He has a .263 batting average and a slugging percentage of .425.
• He is 55th in batting average, 16th in on-base percentage, and 65th in slugging among qualified hitters in the majors.
• Reynolds will look for his fourth straight game with a hit in this contest. In his last five games he is hitting .250 with a double and two walks.
• Brandon Lowe has 123 hits, which leads Pittsburgh batters this season. He's batting .249 with 54 extra-base hits. He's also slugging .470 with an on-base percentage of .316.
• His batting average is 81st among qualified players, his on-base percentage 96th, and his slugging percentage 35th.
• Nick Gonzales leads Pittsburgh in slugging percentage (.394) powered by 29 extra-base hits.
• Spencer Horwitz has 10 home runs, 38 RBI and a batting average of .254 this season.
• Horwitz heads into this matchup on a four-game hitting streak. In his last five games he is hitting .227 with a walk.

Cardinals Player Leaders

• Alec Burleson has racked up a team-high .484 slugging percentage. He's batting .292 with an on-base percentage of .356.
• Including all the qualifying hitters in the big leagues, his batting average is ninth, his on-base percentage ranks 38th, and he is 24th in slugging.
• Burleson hopes to build on a 13-game hitting streak in this matchup. In his last 10 games he is hitting .316 with a double, a walk and seven RBIs.
• Jordan Walker's 146 hits pace his team. He has a batting average of .286 while slugging .502 with an on-base percentage of .345.
• Including all qualified hitters, he ranks 16th in batting average, 50th in on-base percentage and 16th in slugging percentage.
• JJ Wetherholt is batting .245 with 14 doubles, 17 home runs and 63 walks.
• Ivan Herrera's .361 on-base percentage leads his team.

Pirates vs Cardinals Head to Head

• 5/21/2026: 6-2 PIT (Favorite: Pirates, Spread: -1.5, Total: 7, Favorite Moneyline: -122, Underdog Moneyline: +104)
• 5/20/2026: 7-0 PIT (Favorite: Cardinals, Spread: -1.5, Total: 7.5, Favorite Moneyline: -112, Underdog Moneyline: -104)
• 5/19/2026: 9-6 STL (Favorite: Cardinals, Spread: -1.5, Total: 8, Favorite Moneyline: -116, Underdog Moneyline: -102)
• 4/30/2026: 10-5 STL (Favorite: Pirates, Spread: -1.5, Total: 7, Favorite Moneyline: -245, Underdog Moneyline: +200)
• 4/29/2026: 5-4 STL (Favorite: Pirates, Spread: -1.5, Total: 8.5, Favorite Moneyline: -132, Underdog Moneyline: +112)
• 4/28/2026: 11-7 STL (Favorite: Pirates, Spread: -1.5, Total: 8.5, Favorite Moneyline: -162, Underdog Moneyline: +136)
• 4/27/2026: 4-2 STL (Favorite: Pirates, Spread: -1.5, Total: 8, Favorite Moneyline: -122, Underdog Moneyline: +104)
• 8/28/2025: 4-1 STL (Favorite: Cardinals, Spread: -1.5, Total: 8, Favorite Moneyline: -120, Underdog Moneyline: +102)
• 8/27/2025: 2-1 PIT (Favorite: Cardinals, Spread: -1.5, Total: 7.5, Favorite Moneyline: -174, Underdog Moneyline: +146)
• 8/26/2025: 8-3 PIT (Favorite: Cardinals, Spread: -1.5, Total: 8, Favorite Moneyline: -126, Underdog Moneyline: +108)

Sign up for FanDuel Sportsbook and FanDuel Daily Fantasy today!