Phillies vs Rays Prediction, Odds, Moneyline, Spread & Over/Under for Sept. 25

Odds updated as of 6:11 p.m.

On Friday in MLB, the Philadelphia Phillies are up against the Tampa Bay Rays.

Here's everything you need to know before checking out today's MLB odds and spreads on FanDuel Sportsbook.

Phillies vs Rays Game Info

• Philadelphia Phillies (87-72) vs. Tampa Bay Rays (96-63)
• Date: Friday, September 25, 2026
• Time: 6:40 p.m. ET
• Venue: Citizens Bank Park -- Philadelphia, Pennsylvania
• Coverage: NBCS-PH and Rays.TV

Phillies vs Rays Odds & Moneyline

• All MLB odds, betting lines and prop bets are available on FanDuel Sportsbook.
• Moneyline: PHI: (-178) | TB: (+150)
• Spread: PHI: -1.5 (+132) | TB: +1.5 (-160)
• Total: 6.5 -- Over: (-118) | Under: (-104)

Phillies vs Rays Probable Starting Pitchers

Probable Pitchers: Cristopher Sanchez (Phillies) - 18-6, 2.93 ERA vs Freddy Peralta (Rays) - 9-11, 4.56 ERA

The probable pitchers are Cristopher Sanchez (18-6) for the Phillies and Freddy Peralta (9-11) for the Rays. Sanchez's team is 19-13-0 against the spread this season in his starts. Sanchez's team is 23-9 this season when he starts and they are the moneyline favorite. When Peralta starts, the Rays are 16-15-0 against the spread. The Rays have a 5-7 record in Peralta's 12 starts this season when they were the underdog on the moneyline.

Phillies vs Rays Prediction & Pick

All MLB win probability predictions and picks are according to numberFire.
Prediction: Phillies win (54.7%)

Phillies vs Rays Moneyline

• Tampa Bay is the underdog, +150 on the moneyline, while Philadelphia is a -178 favorite at home.

Phillies vs Rays Spread

• The Rays are +1.5 on the spread (-160 to cover), and Philadelphia is +132 to cover the runline.

Phillies vs Rays Over/Under

• The over/under for Phillies-Rays on Sept. 25 is 6.5. The over is -118, and the under is -104.

Bet on Philadelphia Phillies vs. Tampa Bay Rays on FanDuel today!

Phillies vs Rays Betting Trends

• The Phillies have come away with 74 wins in the 115 contests they have been listed as the favorites in this season.
• This year Philadelphia has won 29 of 37 games when listed as at least -178 on the moneyline.
• Contests with the Phillies have gone over the total set by oddsmakers in 74 of 154 chances this season.
• In 154 games with a line this season, the Phillies have a mark of 65-89-0 against the spread.
• The Rays have gone 25-23 in games they were listed as the moneyline underdog (winning 52.1% of those games).
• Tampa Bay has played as a moneyline underdog of +150 or longer in just one game this season, which it lost.
• The Rays have had an over/under set by oddsmakers 157 times, and have combined with opponents to go over the total in 74 of those games (74-81-2).
• The Rays have an 83-74-0 record ATS this season (covering 52.9% of the time).

Phillies Player Leaders

• Bryce Harper has 152 hits this season and a team-best OBP of .381. He has a .270 batting average and a slugging percentage of .486.
• He ranks 42nd in batting average, eighth in on-base percentage, and 20th in slugging among qualifying batters in MLB.
• Luis Arraez has hit six homers this season while driving in 64 runs. He's batting .310 this season and slugging .419 with an on-base percentage of .345.
• He is second in batting average, 47th in on-base percentage and 72nd in slugging in the major leagues.
• Kyle Schwarber leads Philadelphia with 133 hits. He is batting .233 this season and 65 of his hits have gone for extra bases.
• Bryson Stott is batting .249 with a .328 OBP and 66 RBI for Philadelphia this season.

Rays Player Leaders

• Junior Caminero paces the Rays with 167 hits. He's batting .275 and slugging .522 with an on-base percentage of .360.
• He ranks 33rd in batting average, 28th in on-base percentage and fifth in slugging percentage among all qualified hitters in the big leagues.
• Yandy Diaz is slugging .446 to pace his team. He has a batting average of .292 with an on-base percentage of .358.
• Including all qualifying players, he is ninth in batting average, 33rd in on-base percentage and 48th in slugging percentage.
• Liam Hicks has accumulated a team-best .366 on-base percentage.
• Chandler Simpson has 16 doubles, six triples and 26 walks while hitting .308.

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