Patrick Mahomes Fantasy Football Week 16: Stats and Projections vs. Titans

Kansas City Chiefs QB Patrick Mahomes will take on the 25th-ranked pass defense of the Tennessee Titans (233 yards conceded per game) in Week 16, at 1 p.m. ET on Sunday.

With Mahomes' next game versus the Titans, should you think about him for your DFS lineup? Scroll down for more stats and information.

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Patrick Mahomes Week 16 Fantasy Football Projection

• Matchup: Kansas City Chiefs at Tennessee Titans
• Game Date: December 21, 2025
• Game Time: 1 p.m.
• Projected Fantasy Points: 16.9
• Projected Passing Yards: 242.37
• Projected Passing TDs: 1.22
• Projected Rushing Yards: 27.23
• Projected Rushing TDs: 0.18

Projections provided by numberFire

Mahomes Fantasy Performance

• Mahomes has been coming through for fantasy managers this season, as his 284.7 fantasy points (20.3 per game) rank him second at the QB position and second overall.
• In his last three games, Mahomes has compiled 47.8 fantasy points (15.9 per game), connecting on 53-of-95 passes for 610 yards, four touchdowns, and four interceptions. He's added 104 rushing yards on 12 carries with one touchdown on the ground.
• Mahomes has piled up 1,238 passing yards (111-of-186) with five TDs and six picks in his last five games, leading to 78.2 fantasy points (15.6 per game) during that stretch. On the ground, he's contributed 137 yards rushing on 17 carries with one touchdown.
• The peak of Mahomes' fantasy season so far was Week 6 against the Detroit Lions, when he carried 10 times for 32 yards and one touchdown on his way to 31.5 fantasy points.
• From a fantasy standpoint, Patrick Mahomes stumbled to his worst performance of the season in Week 14 against the Houston Texans, throwing for 160 yards and zero touchdowns with three interceptions with 59 yards on seven attempts on the ground (5.3 fantasy points).

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Titans Defensive Performance

• One player has registered more than 300 yards passing in a game against Tennessee this season.
• The Titans have given up at least one passing TD to 13 opposing QBs this season.
• Tennessee has allowed two or more TD passes to nine opposing QBs this season.
• Three players have thrown for at least three TDs in a game versus the Titans this year.
• Tennessee has given up more than 100 yards receiving to three players this season.
• A total of 23 players have caught a TD pass against the Titans this year.
• Tennessee has allowed only two players to catch two or more touchdown passes in a game this year.
• The Titans have allowed just two players to pile up more than 100 yards rushing in a game this season.
• A total of 16 players have run for at least one touchdown against Tennessee this year.
• The Titans have allowed just two players to score more than one rushing touchdown in a game this season.

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