Pacers vs. Cavaliers Prediction, Odds, Picks, Best Bets for Jan. 6

Pacers vs. Cavaliers Game Info

• Date: Tuesday, January 6, 2026
• Time: 7 p.m. ET
• Venue: Gainbridge Fieldhouse -- Indianapolis, Indiana
• Coverage: FDSIN, FDSOH, and Rock Entertainment Sports Network

The Indiana Pacers (6-30) host the Cleveland Cavaliers (20-17) after losing six home games in a row. The Cavaliers are favored by 5.5 points in the contest, which tips at 7 p.m. ET on Tuesday, January 6, 2026. The matchup's over/under is set at 235.5.

Pacers vs. Cavaliers Odds & Spread

All NBA betting lines, odds and prop bets are from FanDuel Sportsbook.

Pacers vs. Cavaliers Prediction & Pick

All NBA win probability predictions and picks are according to numberFire.
Prediction: Cavaliers win (68%)

Pacers vs. Cavaliers Betting Trends

• The Cavaliers have covered the spread in a matchup 13 times this season (13-24-0).
• In the Pacers' 36 games this year, they have 17 wins against the spread.
• Cavaliers games have finished with a final combined score above the over/under 17 times out of 36 chances this season.
• Pacers games this season have gone over the total in 15 of 36 opportunities (41.7%).
• When playing at home, Cleveland owns a worse record against the spread (7-15-0) compared to its ATS record in away games (6-9-0).
• The Cavaliers have hit the over on the over/under in a lower percentage of home games (36.4%) than road games (60%).
• Against the spread, Indiana has been better at home (10-9-0) than away (7-10-0).
• Pacers games have finished above the over/under more often at home (nine times out of 19) than away (six of 17) this year.

Cavaliers Leaders

• Evan Mobley's numbers on the season are 17.7 points, 8.9 boards and 4.0 assists per contest, shooting 50.0% from the floor and 33.6% from downtown, with an average of 1.3 made 3-pointers.
• Jaylon Tyson is averaging 13.1 points, 5.6 rebounds and 1.9 assists. At the other end, he averages 1.0 steal and 0.6 blocked shots.
• De'Andre Hunter averages 14.7 points, 4.3 rebounds and 2.1 assists, shooting 42.4% from the field and 31.6% from beyond the arc, with 1.8 made treys per game.
• Jarrett Allen is averaging 13.7 points, 2.0 assists and 7.8 boards.
• Darius Garland is averaging 17.0 points, 2.6 rebounds and 6.9 assists.

Pacers Leaders

• Pascal Siakam averages 23.8 points, 6.7 rebounds and 3.8 assists. He is also draining 48.7% of his shots from the floor and 37.2% from 3-point range, with 1.7 triples per contest.
• The Pacers get 17.3 points per game from Andrew Nembhard, plus 2.5 boards and 6.8 assists.
• The Pacers are getting 7.8 points, 3.9 boards and 1.3 assists per game from Jay Huff.
• The Pacers are getting 9.0 points, 4.3 rebounds and 1.8 assists per game from Jarace Walker.
• Per game, T.J. McConnell provides the Pacers 9.8 points, 2.5 boards and 4.6 assists, plus 1.1 steals and 0.2 blocks.

For more NBA betting insights, check out FanDuel Research's NBA home page.

Sign up for FanDuel Sportsbook and FanDuel Daily Fantasy today!

Watch FanDuel TV's NBA show "Run It Back" with Lou Williams, Michelle Beadle, DeMarcus "Boogie" Cousins and Chandler Parsons weekdays at 10am ET on FanDuel TV, the Run It Back YouTube page, or download the podcast here: fanduel.com/research/tv-and-podcast.