Oregon vs Oklahoma State Prediction, Odds, Picks, Best Bets for Week 2 2026

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The Oregon Ducks will face the Oklahoma State Cowboys in college football action on Saturday.

Before you make your wager on FanDuel Sportsbook, we've got you covered with all the latest NCAA football betting insights.

Oregon vs Oklahoma State Odds & Spread

All college football odds, betting lines and prop bets are available on FanDuel Sportsbook.
Moneyline: Oregon: (-2326) | Oklahoma State: (+1060)
Spread: Oregon: -23.5 (-105) | Oklahoma State: +23.5 (-115)
Total: 54.5 -- Over: (-110) | Under: (-110)

Oregon is winless against the spread this year.
Oregon has no wins ATS (0-1) as a 23.5-point favorite or greater this season.
Oregon and its opponent have not failed to hit the over in any game this season.
Oklahoma State has no wins against the spread this season.
Oklahoma State and its opponent have yet to go over the total this season.

All college football win probability predictions and picks are according to numberFire.
Prediction: Ducks win (98.5%)

Oregon is favored by 23.5 points against Oklahoma State. Oregon is -105 to cover the spread, while Oklahoma State is -115.

A combined point total of 54.5 has been set for Oregon-Oklahoma State on Sept. 12, with the over at -110 and the under at -110.

Looking at the moneyline for Oregon-Oklahoma State, Oregon is the favorite at -2326, and Oklahoma State is +1060.

The Ducks had an average implied point total of 34.3 last season, which is 4.7 points lower than their implied total in Saturday's game (39).
The average implied point total last season for the Cowboys (37.6) is 21.6 more points than the team's implied total in this matchup (16).

Check out even more in-depth Oregon vs. Oklahoma State analysis on FanDuel Research.

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