Oregon vs Oklahoma State Prediction, Odds, Picks, Best Bets for Week 2 2026

The Oregon Ducks will face the Oklahoma State Cowboys in college football action on Saturday.

We've got you covered, in terms of the vital info about NCAA football betting lines, before you make your wager on FanDuel Sportsbook.

Oregon vs Oklahoma State Odds & Spread

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• All college football odds, betting lines and prop bets are available on FanDuel Sportsbook.
• Moneyline: Oregon: (-2500) | Oklahoma State: (+1100)
• Spread: Oregon: -23.5 (-108) | Oklahoma State: +23.5 (-112)
• Total: 55.5 -- Over: (-110) | Under: (-110)

Oregon vs Oklahoma State Betting Trends

• Oregon is winless against the spread this year.
• Oregon has yet to win ATS (0-1) when playing as at least 23.5-point favorites this year.
• One of one Oregon games have gone over the point total this year.
• Oklahoma State has not won a game against the spread this year.
• No Oklahoma State game has hit the over this season.

Oregon vs Oklahoma State Prediction & Pick

All college football win probability predictions and picks are according to numberFire.
Prediction: Ducks win (98.5%)

Oregon vs Oklahoma State Point Spread

Oklahoma State is a 23.5-point underdog against Oregon. Oklahoma State is -112 to cover the spread, and Oregon is -108.

Oregon vs Oklahoma State Over/Under

The Oregon-Oklahoma State game on Sept. 12 has been given an over/under of 55.5 points. The over is -110 and the under is -110.

Oregon vs Oklahoma State Moneyline

Oklahoma State is the underdog, +1100 on the moneyline, while Oregon is a -2500 favorite.

Oregon vs. Oklahoma State Points Insights

• The average implied total for the Ducks last season was 34.3 points, 5.7 fewer points than their implied total of 40 points in Saturday's game.
• The 37.6-point average implied total last season for the Cowboys is 21.6 more points than the team's 16-point implied total in this matchup.

Oregon vs. Oklahoma State Game Info

• Game day: Saturday, September 12, 2026
• Game time: 12 p.m. ET
• TV channel: ESPN
• Location: Stillwater, Oklahoma
• Stadium: Boone Pickens Stadium

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Check out even more in-depth Oregon vs. Oklahoma State analysis on FanDuel Research.