Oklahoma vs Michigan Prediction, Odds, Picks, Best Bets for Week 2 2026

The Oklahoma Sooners versus the Michigan Wolverines is on the college football schedule for Saturday.

Before you place your bet on this matchup at FanDuel Sportsbook, here are the NCAA football odds and spreads you need to know.

Oklahoma vs Michigan Odds & Spread

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• All college football odds, betting lines and prop bets are available on FanDuel Sportsbook.
• Moneyline: Oklahoma: (-200) | Michigan: (+168)
• Spread: Oklahoma: -4.5 (-114) | Michigan: +4.5 (-106)
• Total: 43.5 -- Over: (-108) | Under: (-112)

Oklahoma vs Michigan Betting Trends

• Oklahoma has posted one win against the spread this year.
• Oklahoma has covered every time (1-0) as a 4.5-point favorite or greater this year.
• Oklahoma has had one game (of one) hit the over this year.
• Michigan has not won a game against the spread this season.
• No Michigan game has gone over the point total this season.

Oklahoma vs Michigan Prediction & Pick

All college football win probability predictions and picks are according to numberFire.
Prediction: Sooners win (50.8%)

Oklahoma vs Michigan Point Spread

Oklahoma is favored by 4.5 points (-114 to cover) in this matchup. Michigan, the underdog, is -106.

Oklahoma vs Michigan Over/Under

The Oklahoma-Michigan game on Sept. 12 has been given an over/under of 43.5 points. The over is -108 and the under is -112.

Oklahoma vs Michigan Moneyline

Oklahoma is the favorite, -200 on the moneyline, while Michigan is a +168 underdog.

Oklahoma vs. Michigan Points Insights

• The average implied total for the Sooners last season was 30.1 points, 6.1 more points than their implied total of 24 points in Saturday's game.
• The average implied point total last season for the Wolverines (30.0) is 10.0 more points than the team's implied total in this matchup (20).

Oklahoma vs. Michigan Game Info

• Game day: Saturday, September 12, 2026
• Game time: 12 p.m. ET
• TV channel: FOX
• Location: Ann Arbor, Michigan
• Stadium: Michigan Stadium

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Check out even more in-depth Oklahoma vs. Michigan analysis on FanDuel Research.