Oklahoma vs Michigan Prediction, Odds, Picks, Best Bets for Week 2 2026

The Saturday slate in college football includes a matchup between the Oklahoma Sooners and the Michigan Wolverines.

Before you make your wager on FanDuel Sportsbook, we've got you covered, in terms of the most important information about today's NCAA football betting odds.

Oklahoma vs Michigan Odds & Spread

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• All college football odds, betting lines and prop bets are available on FanDuel Sportsbook.
• Moneyline: Oklahoma: (-210) | Michigan: (+176)
• Spread: Oklahoma: -5.5 (-110) | Michigan: +5.5 (-110)
• Total: 43.5 -- Over: (-110) | Under: (-110)

Oklahoma vs Michigan Betting Trends

• Oklahoma hasn't lost a game against the spread this year.
• Oklahoma is unbeaten ATS (1-0) as a 5.5-point favorite or greater this season.
• Oklahoma has had one game (of one) hit the over this year.
• Michigan has not won a game against the spread this year.
• None of Michigan's one games has hit the over in 2026.

Oklahoma vs Michigan Prediction & Pick

All college football win probability predictions and picks are according to numberFire.
Prediction: Sooners win (55.6%)

Oklahoma vs Michigan Point Spread

Michigan is a 5.5-point underdog against Oklahoma. Michigan is -110 to cover the spread, and Oklahoma is -110.

Oklahoma vs Michigan Over/Under

The over/under for the Oklahoma versus Michigan matchup on Sept. 12 has been set at 43.5, with -110 odds on the over and -110 odds on the under.

Oklahoma vs Michigan Moneyline

Michigan is a +176 underdog on the moneyline, while Oklahoma is a -210 favorite.

Oklahoma vs. Michigan Points Insights

• The average implied total for the Sooners last season was 30.1 points, 5.1 more points than their implied total of 25 points in Saturday's game.
• The 30.0-point average implied total last season for the Wolverines is 11.0 more points than the team's 19-point implied total in this matchup.

Oklahoma vs. Michigan Game Info

• Game day: Saturday, September 12, 2026
• Game time: 12 p.m. ET
• TV channel: FOX
• Location: Ann Arbor, Michigan
• Stadium: Michigan Stadium

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Check out even more in-depth Oklahoma vs. Michigan analysis on FanDuel Research.