Ohio State vs UCLA Prediction, Odds, Picks, Best Bets for Week 12 2025

Saturday's slate in college football includes a matchup between the Ohio State Buckeyes and the UCLA Bruins.

We've got you covered, in terms of the vital information regarding NCAA football betting lines, before you make your wager on FanDuel Sportsbook.

Ohio State vs UCLA Odds & Spread

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• All college football odds, betting lines and prop bets are available on FanDuel Sportsbook.
• Moneyline: Ohio State: (-33333) | UCLA: (+4000)
• Spread: Ohio State: -34.5 (-105) | UCLA: +34.5 (-115)
• Total: 47.5 -- Over: (-105) | Under: (-115)

Ohio State vs UCLA Betting Trends

• Ohio State has beaten the spread seven times in nine games.
• Ohio State has yet to lose ATS (1-0) as a 34.5-point favorite or greater this year.
• Ohio State has played nine games this year, and three of them have hit the over.
• UCLA is 3-6-0 against the spread this season.
• UCLA has played nine games this season, and four of them have hit the over.

Ohio State vs UCLA Prediction & Pick

All college football win probability predictions and picks are according to numberFire.
Prediction: Buckeyes win (97.4%)

Ohio State vs UCLA Point Spread

UCLA is listed as an underdog by 34.5 points (-115 odds), and Ohio State, the favorite, is -105 to cover.

Ohio State vs UCLA Over/Under

Ohio State versus UCLA, on Nov. 15, has an over/under of 47.5, with the over being -105 and the under -115.

Ohio State vs UCLA Moneyline

The Ohio State vs UCLA moneyline has Ohio State as a -33333 favorite, while UCLA is a +4000 underdog.

Ohio State vs. UCLA Points Insights

Ohio State vs. UCLA Game Info

• Game day: Saturday, November 15, 2025
• Game time: 7:30 p.m. ET
• TV channel: NBC
• Location: Columbus, Ohio
• Stadium: Ohio Stadium

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Check out even more in-depth Ohio State vs. UCLA analysis on FanDuel Research.