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Isaac Guerendo
San Francisco 49ers • #31 • RB
Isaac Guerendo Active for Week 1 Against Seahawks With Back Injury
Isaac Guerendo participated fully in practice on Wednesday and is listed as probable for Week 1 against the Seahawks.
What It Means
Guerendo, drafted by the 49ers in 2024, has logged 16 games during the 2024 regular season, with 420 rushing yards, 4 rushing TDs, and 5 yards per attempt. In the 2025 preseason, he played 3 games, totaling 14 yards on 9 touches. The 49ers face the Seahawks at Lumen Field on September 7, 2025, for Week 1 of the regular season.
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