Sunday’s MLB Strikeout Props - Sept. 27

Will Kade Anderson strike out more than 5.5 batters? Can Hayden Wesneski exceed 3.5 strikeouts? See their odds and more strikeout prop odds for all pitchers in MLB play on Sept. 27, in the article below.

Today's MLB Strikeout Props

Los Angeles Angels at Seattle Mariners

• Kade Anderson (Mariners): Over/Under 5.5 Ks (Over -146, Under +114) | 2026 Stats: 4.7 strikeouts per game in 6 appearances
• Ryan Johnson (Angels): Over/Under 4.5 Ks (Over +112, Under -142) | 2026 Stats: 3.6 strikeouts per game in 21 appearances

Arizona Diamondbacks at San Diego Padres

• Walker Buehler (Padres): Over/Under 3.5 Ks (Over -125, Under -102) | 2026 Stats: 4.1 strikeouts per game in 31 appearances

Houston Astros at Athletics

• Jack Perkins (Athletics): Over/Under 4.5 Ks (Over -113, Under -113) | 2026 Stats: 3.6 strikeouts per game in 36 appearances
• Hayden Wesneski (Astros): Over/Under 3.5 Ks (Over -150, Under +118) | 2026 Stats: 4.1 strikeouts per game in 10 appearances