Michigan vs Iowa Prediction, Odds, Picks, Best Bets for Week 4 2026

On Saturday in college football, the Michigan Wolverines are up against the Iowa Hawkeyes.

Before you make your wager on FanDuel Sportsbook, we've got you covered with all the latest NCAA football betting insights.

Michigan vs Iowa Odds & Spread

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• All college football odds, betting lines and prop bets are available on FanDuel Sportsbook.
• Moneyline: Michigan: (-215) | Iowa: (+176)
• Spread: Michigan: -5.5 (-110) | Iowa: +5.5 (-110)
• Total: 39.5 -- Over: (-110) | Under: (-110)

Michigan vs Iowa Betting Trends

• Michigan has won twice against the spread this season.
• As a 5.5-point or greater favorite, Michigan has one win ATS (1-1) this season.
• One of three Michigan games have gone over the point total this year.
• Iowa owns two wins against the spread this year.
• One of Iowa's three games has hit the over.

Michigan vs Iowa Prediction & Pick

All college football win probability predictions and picks are according to numberFire.
Prediction: Wolverines win (58.9%)

Michigan vs Iowa Point Spread

Michigan is favored by 5.5 points over Iowa. Michigan is -110 to cover the spread, with Iowa being -110.

Michigan vs Iowa Over/Under

Michigan versus Iowa, on Sept. 26, has an over/under of 39.5, with the over being -110 and the under -110.

Michigan vs Iowa Moneyline

Michigan is the favorite, -215 on the moneyline, while Iowa is a +176 underdog.

Michigan vs. Iowa Points Insights

Michigan vs. Iowa Game Info

• Game day: Saturday, September 26, 2026
• Game time: 3:30 p.m. ET
• TV channel: CBS
• Location: Ann Arbor, Michigan
• Stadium: Michigan Stadium

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Check out even more in-depth Michigan vs. Iowa analysis on FanDuel Research.