Mavericks vs. Grizzlies Prediction, Odds, Picks, Best Bets for Nov. 22

Mavericks vs. Grizzlies Game Info

• Date: Saturday, November 22, 2025
• Time: 8:30 p.m. ET
• Venue: American Airlines Center -- Dallas, Texas
• Coverage: KFAA and FDSSE

The Memphis Grizzlies (5-11) are slight underdogs (by 2.5 points) to break a five-game road losing streak when they visit the Dallas Mavericks (5-12) on Saturday, November 22, 2025 at 8:30 p.m. ET. The matchup has an over/under of 226.5 points.

Mavericks vs. Grizzlies Odds & Spread

All NBA betting lines, odds and prop bets are from FanDuel Sportsbook.

Mavericks vs. Grizzlies Prediction & Pick

All NBA win probability predictions and picks are according to numberFire.
Prediction: Grizzlies win (58.6%)

Mavericks vs. Grizzlies Betting Trends

• The Mavericks have put together a 7-10-0 record against the spread this season.
• In the Grizzlies' 16 games this year, they have five wins against the spread.
• This season, six of the Mavericks' games have gone over the point total out of 16 chances.
• Grizzlies games this year have gone over the point total 31.2% of the time (five out of 16 games with a set point total).
• At home, Dallas owns a better record against the spread (5-7-0) compared to its ATS record on the road (2-3-0).
• When it comes to over/unders, the Mavericks hit the over more often in home games, as they've gone over the total five times in 12 opportunities this season (41.7%). In road games, they have hit the over one time in five opportunities (20%).
• In 2025-26 against the spread, Memphis has a better winning percentage at home (.444, 4-5-0 record) than on the road (.143, 1-6-0).
• In terms of the over/under, Grizzlies games have gone over three of nine times at home (33.3%), and two of seven on the road (28.6%).

Mavericks Leaders

• Cooper Flagg is averaging 16.4 points, 6.4 boards and 3.3 assists. At the other end, he averages 1.3 steals and 0.7 blocked shots.
• P.J. Washington averages 15 points, 7.8 boards and 2.3 assists, shooting 43.4% from the floor and 33.3% from beyond the arc, with 1.5 made 3-pointers per contest.
• Naji Marshall is averaging 11.8 points, 4.8 rebounds and 2.4 assists. At the other end, he averages 1.1 steals and 0 blocked shots.
• Max Christie's numbers on the season are 12.9 points, 3.5 rebounds and 2.4 assists per game, shooting 48.4% from the field and 46.9% from downtown (eighth in NBA), with an average of 2.7 made 3-pointers.
• D'Angelo Russell is averaging 12.6 points, 5 assists and 2.9 rebounds.

Grizzlies Leaders

• Cedric Coward averages 14.6 points for the Grizzlies, plus 6.3 boards and 2.9 assists.
• Santi Aldama's numbers on the season are 13.5 points, 6.7 boards and 2.4 assists per game. He is sinking 47.5% of his shots from the floor and 32.5% from 3-point range, with an average of 1.6 triples.
• The Grizzlies receive 17.9 points per game from Jaren Jackson Jr., plus 5.3 rebounds and 1.5 assists.
• Jock Landale's numbers on the season are 10.6 points, 5.6 boards and 1.6 assists per contest. He is sinking 54.5% of his shots from the field and 43.6% from 3-point range, with an average of 1.1 treys.
• The Grizzlies get 9 points per game from Cam Spencer, plus 2 rebounds and 3.2 assists.

For more NBA betting insights, check out FanDuel Research's NBA home page.

Sign up for FanDuel Sportsbook and FanDuel Daily Fantasy today!

Watch FanDuel TV's NBA show "Run It Back" with Lou Williams, Michelle Beadle, DeMarcus "Boogie" Cousins and Chandler Parsons weekdays at 10am ET on FanDuel TV, the Run It Back YouTube page, or download the podcast here: fanduel.com/research/tv-and-podcast.