Marshall vs Appalachian State Prediction, Odds, Picks, Best Bets for Week 13 2025

Saturday's slate in college football includes a matchup between the Marshall Thundering Herd and the Appalachian State Mountaineers.

Before you make your wager on FanDuel Sportsbook, we've got you covered with all the latest NCAA football betting insights.

Marshall vs Appalachian State Odds & Spread

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• All college football odds, betting lines and prop bets are available on FanDuel Sportsbook.
• Moneyline: Marshall: (-200) | Appalachian State: (+168)
• Spread: Marshall: -4.5 (-115) | Appalachian State: +4.5 (-105)
• Total: 56.5 -- Over: (-115) | Under: (-105)

Marshall vs Appalachian State Betting Trends

• Marshall has seven wins in 10 games against the spread this season.
• Marshall has two wins ATS (2-2) as a 4.5-point or higher favorite in 2025.
• This season, seven of Marshall's 10 games have go over the point total.
• Appalachian State is 4-6-0 against the spread this year.
• Appalachian State has one win ATS (1-2) as a 4.5-point underdog or greater this season.
• Appalachian State has seen five of its 10 games hit the over.

Marshall vs Appalachian State Prediction & Pick

All college football win probability predictions and picks are according to numberFire.
Prediction: Thundering Herd win (68.5%)

Marshall vs Appalachian State Point Spread

Appalachian State is a 4.5-point underdog against Marshall. Appalachian State is -105 to cover the spread, and Marshall is -115.

Marshall vs Appalachian State Over/Under

The over/under for the Marshall versus Appalachian State matchup on Nov. 22 has been set at 56.5, with -115 odds on the over and -105 odds on the under.

Marshall vs Appalachian State Moneyline

The moneyline numbers for Marshall vs. Appalachian State reveal Marshall as the favorite (-200) and Appalachian State as the underdog (+168).

Marshall vs. Appalachian State Points Insights

Marshall vs. Appalachian State Game Info

• Game day: Saturday, November 22, 2025
• Game time: 2:30 p.m. ET
• TV channel: ESPN+
• Location: Boone, North Carolina
• Stadium: Kidd Brewer Stadium

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Check out even more in-depth Marshall vs. Appalachian State analysis on FanDuel Research.