LSU vs Kentucky Prediction, Odds, Picks, Best Bets for Week 6 2026

NCAA football action on Saturday includes the LSU Tigers facing the Kentucky Wildcats.

We've got you covered, in terms of the vital info regarding NCAA football betting lines, before you make your wager on FanDuel Sportsbook.

LSU vs Kentucky Odds & Spread

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• All college football odds, betting lines and prop bets are available on FanDuel Sportsbook.
• Moneyline: LSU: (-334) | Kentucky: (+265)
• Spread: LSU: -8.5 (-110) | Kentucky: +8.5 (-110)
• Total: 51.5 -- Over: (-118) | Under: (-104)

LSU vs Kentucky Betting Trends

• LSU has two wins against the spread this season.
• LSU has two wins ATS (2-2) as an 8.5-point or higher favorite in 2026.
• There have been three LSU games (of five) that went over the total this year.
• Kentucky has covered the spread four times in five games.
• Kentucky has one win ATS (1-1) as an 8.5-point underdog or more this year.
• Kentucky has played five games this year, and four of them have gone over the total.

LSU vs Kentucky Prediction & Pick

All college football win probability predictions and picks are according to numberFire.
Prediction: Tigers win (66.8%)

LSU vs Kentucky Point Spread

LSU is favored by 8.5 points over Kentucky. LSU is -110 to cover the spread, with Kentucky being -110.

LSU vs Kentucky Over/Under

LSU versus Kentucky, on Oct. 10, has an over/under of 51.5, with the over being -118 and the under -104.

LSU vs Kentucky Moneyline

The LSU vs Kentucky moneyline has LSU as a -334 favorite, while Kentucky is a +265 underdog.

LSU vs. Kentucky Points Insights

LSU vs. Kentucky Game Info

• Game day: Saturday, October 10, 2026
• Game time: 7 p.m. ET
• TV channel: ESPN
• Location: Lexington, Kentucky
• Stadium: Kroger Field

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Check out even more in-depth LSU vs. Kentucky analysis on FanDuel Research.