LSU vs Alabama Prediction, Odds, Picks, Best Bets for Week 10 2026

The Saturday schedule in college football includes a matchup between the LSU Tigers and the Alabama Crimson Tide.

Before you place your bet on this game at FanDuel Sportsbook, here are the NCAA football odds and spreads you need to know.

LSU vs Alabama Odds & Spread

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• All college football odds, betting lines and prop bets are available on FanDuel Sportsbook.
• Moneyline: LSU: (-220) | Alabama: (+184)
• Spread: LSU: -5.5 (-115) | Alabama: +5.5 (-105)
• Total: 52.5 -- Over: (-115) | Under: (-105)

LSU vs Alabama Betting Trends

• LSU is 4-4-0 against the spread this year.
• LSU owns an ATS record of 4-3 as 5.5-point or greater favorites.
• This year, five of LSU's eight games have hit the over.
• Against the spread, Alabama is 4-4-0 this season.
• This year, six of Alabama's eight games have hit the over.

LSU vs Alabama Prediction & Pick

All college football win probability predictions and picks are according to numberFire.
Prediction: Tigers win (67.2%)

LSU vs Alabama Point Spread

LSU is a 5.5-point favorite against Alabama. LSU is -115 to cover the spread, and Alabama is -105.

LSU vs Alabama Over/Under

An over/under of 52.5 has been set for LSU-Alabama on Nov. 7, with the over being -115 and the under -105.

LSU vs Alabama Moneyline

The moneyline numbers for LSU vs. Alabama reveal LSU as the favorite (-220) and Alabama as the underdog (+184).

LSU vs. Alabama Points Insights

LSU vs. Alabama Game Info

• Game day: Saturday, November 7, 2026
• Game time: 3:30 p.m. ET
• TV channel: ABC
• Location: Baton Rouge, Louisiana
• Stadium: Tiger Stadium

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Check out even more in-depth LSU vs. Alabama analysis on FanDuel Research.