Louisville vs Virginia Tech College Basketball Prediction, Odds, Picks, Best Bets for Jan. 24

ACC play on Saturday will see the the No. 23 Louisville Cardinals (13-5, 3-3 ACC) host the Virginia Tech Hokies (15-5, 4-3 ACC) at KFC Yum! Center, tipping off at 2:15 p.m. ET.

Before you place your bet on this matchup at FanDuel Sportsbook, here are the NCAA basketball odds and spreads you need to know.

Louisville vs. Virginia Tech Game Info and Odds

• Game day: Saturday, January 24, 2026
• Game time: 2:15 p.m. ET
• TV channel: The CW Network
• Location: Louisville, Kentucky
• Arena: KFC Yum! Center

Before you decide to wager on Louisville-Virginia Tech contest (in which Louisville is a 13.5-point favorite and the total has been set at 159.5 points), here are a few betting trends and insights for Saturday's game.

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Louisville vs. Virginia Tech: ATS Betting Stats and Trends

• Louisville has won 10 games against the spread this season, while failing to cover eight times.
• Virginia Tech has compiled a 12-8-0 ATS record so far this year.
• At home, the Cardinals have a better record against the spread (6-5-0) compared to their ATS record in road games (2-3-0).
• The Hokies' winning percentage against the spread at home is .583 (7-5-0). Away, it is 1.000 (4-0-0).
• Louisville has two wins against the spread in conference play this year.
• Virginia Tech has covered the spread five times in seven ACC games.

Louisville vs. Virginia Tech: Moneyline Betting Stats

• Louisville has been the moneyline favorite in 10 games this season and has come away with the win seven times (70%) in those contests.
• The Cardinals have been listed as a favorite of -1408 or more on two occasions this season and won both games.
• Virginia Tech has won 50% of the games this season it was the underdog on the moneyline (4-4).
• The Hokies have yet to play as a moneyline underdog of +800 or longer.
• Sportsbooks have implied with the moneyline set for this matchup that Louisville has a 93.4% chance of pulling out a win.

Louisville vs. Virginia Tech Head-to-Head Comparison

• Louisville's +331 scoring differential (outscoring opponents by 18.3 points per game) is a result of scoring 87.9 points per game (18th in college basketball) while allowing 69.6 per outing (76th in college basketball).
• Ryan Conwell paces Louisville, putting up 19.8 points per game (40th in the nation).
• Virginia Tech puts up 82 points per game (81st in college basketball) while allowing 74.1 per contest (200th in college basketball). It has a +159 scoring differential and outscores opponents by 7.9 points per game.
• Amani Hansberry leads Virginia Tech, averaging 15.5 points per game (247th in college basketball).
• The Cardinals win the rebound battle by 8.6 boards on average. They record 38.9 rebounds per game, which ranks ninth in college basketball, while their opponents grab 30.3 per outing.
• Sananda Fru paces the team with 6.9 rebounds per game (169th in college basketball play).
• The Hokies prevail in the rebound battle by an average of 1.5 boards. They are collecting 33.8 rebounds per game (114th in college basketball) compared to their opponents' 32.3.
• Hansberry is 48th in college basketball with 8.6 rebounds per game, leading the Hokies.
• Louisville ranks 20th in college basketball with 108.2 points scored per 100 possessions, and 31st in college basketball defensively with 85.6 points conceded per 100 possessions.
• The Hokies put up 100.5 points per 100 possessions (119th in college basketball), while giving up 90.7 points per 100 possessions (106th in college basketball).

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