Kansas vs Notre Dame College Basketball Prediction, Odds, Picks, Best Bets for Nov. 24

The Notre Dame Fighting Irish (4-1) will attempt to continue a four-game home winning streak when they host the Kansas Jayhawks (3-2) on November 24, 2025 at MGM Grand Garden Arena.

Before you place your bet on this game at FanDuel Sportsbook, here are the NCAA basketball odds and spreads you need to know.

Kansas vs. Notre Dame Game Info and Odds

• Game day: Monday, November 24, 2025
• Game time: 3:30 p.m. ET
• TV channel: TNT
• Location: Las Vegas, Nevada
• Arena: MGM Grand Garden Arena

Kansas vs. Notre Dame Picks and Prediction

All college basketball win probability predictions and picks are according to numberFire.
Prediction: Kansas win (72.8%)

Before you bet on Monday's Kansas-Notre Dame spread (Kansas -4.5) or total (141.5 points), take a look at the betting trends and insights below.

Sign up for FanDuel Sportsbook and FanDuel Daily Fantasy today!

Kansas vs. Notre Dame: ATS Betting Stats and Trends

• Kansas has won two games against the spread this season.
• Notre Dame has covered twice in four games with a spread this season.
• Notre Dame covers the spread when it is a 4.5-point underdog or more 100% of the time. That's more often than Kansas covers as a favorite of 4.5 or more (66.7%).
• The Jayhawks did a better job covering the spread at home (8-9-0) last season than they did in road games (5-7-0).
• The Fighting Irish's winning percentage against the spread at home last season was .438 (7-9-0). On the road, it was .417 (5-7-0).

Kansas vs. Notre Dame: Moneyline Betting Stats

• Kansas has won in each of the two matchups it has played as moneyline favorites this season.
• The Jayhawks have been listed as a favorite of -235 or more on two occasions this season and won both games.
• Notre Dame has been listed as the moneyline underdog just one other time so far this season, a game it lost.
• The Fighting Irish have played as a moneyline underdog of +190 or longer in just one game this season, which they lost.
• The moneyline set for this matchup implies Kansas has a 70.1% chance of walking away with the win.

Kansas vs. Notre Dame Head-to-Head Comparison

• Kansas' +68 scoring differential (outscoring opponents by 13.6 points per game) is a result of scoring 77.4 points per game (209th in college basketball) while giving up 63.8 per contest (38th in college basketball).
• Flory Bidunga's 16.4 points per game lead Kansas and are 208th in the nation.
• Notre Dame has a +80 scoring differential, topping opponents by 16 points per game. It is putting up 83.6 points per game, 113th in college basketball, and is giving up 67.6 per outing to rank 81st in college basketball.
• Markus Burton is ranked 61st in the nation with a team-high 19.4 points per game.
• The Jayhawks grab 35.4 rebounds per game (133rd in college basketball) while conceding 28.8 per outing to their opponents. They outrebound opponents by 6.6 boards per game.
• Bidunga paces the team with 7.4 rebounds per game (159th in college basketball play).
• The Fighting Irish rank 125th in college basketball at 35.6 rebounds per game. That's 11.2 more than the 24.4 their opponents average.
• Carson Towt tops the team with 12.6 rebounds per game (fourth in college basketball).
• Kansas puts up 102.5 points per 100 possessions (108th in college basketball), while allowing 84.5 points per 100 possessions (92nd in college basketball).
• The Fighting Irish's 110 points per 100 possessions on offense rank 36th in college basketball, and the 89 points they concede per 100 possessions rank 156th in college basketball.

Sign up for FanDuel Sportsbook and FanDuel Daily Fantasy today!