Iowa State vs Houston College Basketball Prediction, Odds, Picks, Best Bets for Feb. 16

The Houston Cougars (23-2, 11-1 Big 12) will look to build on a six-game winning streak when they visit the Iowa State Cyclones (22-3, 9-3 Big 12) on February 16, 2026 at James H. Hilton Coliseum.

Before you place your bet on this matchup at FanDuel Sportsbook, here are the NCAA basketball odds and spreads you need to know.

Iowa State vs. Houston Game Info and Odds

• Game day: Monday, February 16, 2026
• Game time: 9 p.m. ET
• TV channel: ESPN
• Location: Ames, Iowa
• Arena: James H. Hilton Coliseum

Take a look at some betting trends for Iowa State (-2.5) versus Houston on Monday. The over/under has been set at 135.5 points for this game.

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Iowa State vs. Houston: ATS Betting Stats and Trends

• Iowa State has covered 14 times in 25 games with a spread this season.
• Houston has compiled a 14-11-0 ATS record so far this year.
• The Cyclones have a worse record against the spread when playing at home (7-7-0) than they do in away games (4-3-0).
• In 2025-26 against the spread, the Cougars have a lower winning percentage at home (.615, 8-5-0 record) than on the road (.667, 4-2-0).
• Iowa State has beaten the spread seven times in 12 conference games.
• Against the spread in Big 12 games, Houston is 8-4-0 this season.

Iowa State vs. Houston: Moneyline Betting Stats

• Iowa State has been the moneyline favorite in 20 games this season and has come away with the win 17 times (85%) in those contests.
• This season, the Cyclones have come away with a win 17 times in 20 chances when named as a favorite of at least -140 or better on the moneyline.
• Houston has not played as the moneyline underdog so far this season.
• The Cougars have yet to play a game with moneyline odds of +116 or longer.
• Iowa State has an implied victory probability of 58.3% according to the moneyline set by sportsbooks for this matchup.

Iowa State vs. Houston Head-to-Head Comparison

• Iowa State has a +492 scoring differential, topping opponents by 19.7 points per game. It is putting up 84.2 points per game to rank 31st in college basketball and is allowing 64.5 per outing to rank 10th in college basketball.
• Milan Momcilovic paces Iowa State, recording 18.4 points per game (78th in the nation).
• Houston's +425 scoring differential (outscoring opponents by 17 points per game) is a result of putting up 78.3 points per game (129th in college basketball) while giving up 61.3 per outing (second in college basketball).
• Emanuel Sharp's 16.6 points per game leads Houston and ranks 175th in college basketball.
• The Cyclones grab 33.4 rebounds per game (113th in college basketball) while allowing 27.4 per outing to their opponents. They outrebound opponents by six boards per game.
• Joshua Jefferson tops the Cyclones with 7.6 rebounds per game (96th in college basketball play).
• The Cougars pull down 33 rebounds per game (131st in college basketball) while allowing 28.6 per contest to opponents. They outrebound opponents by 4.4 boards per game.
• Chris Cenac Jr. leads the team with 7.4 rebounds per game (110th in college basketball).
• Iowa State averages 108.2 points per 100 possessions on offense (19th in college basketball), and allows 82.9 points per 100 possessions (eighth in college basketball).
• The Cougars put up 103.8 points per 100 possessions (58th in college basketball), while conceding 81.2 points per 100 possessions (first in college basketball).

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